Rescue radical trachelectomy for preservation of fertility in benign disease

Objectives To report a series of patients treated with modified radical abdominal trachelectomy to preserve fertility in benign disease that would normally result in hysterectomy. Design We reviewed all cases of radical abdominal trachelectomy performed for nonneoplastic indications. Patient(s) Of t...

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Veröffentlicht in:Fertility and sterility 2010-10, Vol.94 (5), p.1910.e5-1910.e7
Hauptverfasser: Del Priore, Giuseppe, M.D., M.P.H, Klapper, Allan S., M.D, Gurshumov, Emil, M.D, Vargas, Marino Martinez, M.D, Ungar, Laszlo, M.D, Smith, J. Richard, M.D
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container_end_page 1910.e7
container_issue 5
container_start_page 1910.e5
container_title Fertility and sterility
container_volume 94
creator Del Priore, Giuseppe, M.D., M.P.H
Klapper, Allan S., M.D
Gurshumov, Emil, M.D
Vargas, Marino Martinez, M.D
Ungar, Laszlo, M.D
Smith, J. Richard, M.D
description Objectives To report a series of patients treated with modified radical abdominal trachelectomy to preserve fertility in benign disease that would normally result in hysterectomy. Design We reviewed all cases of radical abdominal trachelectomy performed for nonneoplastic indications. Patient(s) Of the >160 radical abdominal trachelectomies we performed, four cases were performed for benign indications. One patient had a 10-year history of progressive endometriosis with worsening hydronephrosis, failed medical therapy, and infertility. Two myomectomy patients had intraoperative consultation and a third had preoperative consultation for large lower segment/cervical myomas with conversion to trachelectomy rather than hysterectomy. Intervention(s) Modified radical trachelectomy was successfully completed in all patients. Main Outcome Measure(s) We measured the successful completion of the surgery without hysterectomy, complications, and follow-up. Result(s) Hysterectomy was avoided in all patients, and all resumed normal menses. There were no intraoperative or postoperative complications. One required hysterectomy for recurrence 1 year later, and the remainder were symptom free at 1–5 years of follow-up. Conclusion(s) Although traditionally performed with cervical cancer, radical abdominal trachelectomy can be modified to preserve fertility for benign indications that would otherwise require hysterectomy.
doi_str_mv 10.1016/j.fertnstert.2010.03.019
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Intervention(s) Modified radical trachelectomy was successfully completed in all patients. Main Outcome Measure(s) We measured the successful completion of the surgery without hysterectomy, complications, and follow-up. Result(s) Hysterectomy was avoided in all patients, and all resumed normal menses. There were no intraoperative or postoperative complications. One required hysterectomy for recurrence 1 year later, and the remainder were symptom free at 1–5 years of follow-up. 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Richard, M.D</creatorcontrib><title>Rescue radical trachelectomy for preservation of fertility in benign disease</title><title>Fertility and sterility</title><addtitle>Fertil Steril</addtitle><description>Objectives To report a series of patients treated with modified radical abdominal trachelectomy to preserve fertility in benign disease that would normally result in hysterectomy. Design We reviewed all cases of radical abdominal trachelectomy performed for nonneoplastic indications. Patient(s) Of the &gt;160 radical abdominal trachelectomies we performed, four cases were performed for benign indications. One patient had a 10-year history of progressive endometriosis with worsening hydronephrosis, failed medical therapy, and infertility. Two myomectomy patients had intraoperative consultation and a third had preoperative consultation for large lower segment/cervical myomas with conversion to trachelectomy rather than hysterectomy. Intervention(s) Modified radical trachelectomy was successfully completed in all patients. Main Outcome Measure(s) We measured the successful completion of the surgery without hysterectomy, complications, and follow-up. Result(s) Hysterectomy was avoided in all patients, and all resumed normal menses. There were no intraoperative or postoperative complications. One required hysterectomy for recurrence 1 year later, and the remainder were symptom free at 1–5 years of follow-up. 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source MEDLINE; Access via ScienceDirect (Elsevier); EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection
subjects Adult
Endometriosis - surgery
Female
Fertility
fertility preservation
Follow-Up Studies
Gynecologic Surgical Procedures - methods
Humans
Hydronephrosis - surgery
Internal Medicine
Leiomyoma - surgery
Myoma - surgery
Obstetrics and Gynecology
Radical abdominal trachelectomy
Treatment Outcome
Uterine Diseases - surgery
Uterine Neoplasms - surgery
uterine preservation
title Rescue radical trachelectomy for preservation of fertility in benign disease
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