Allelic variations clustered in the antigen binding sites of HLA-Bw62 molecules

HLA-Bw62 is a serologically defined class I antigen specificity, but we show that it represents a family of five distinct alleles in this study. Five variants of HLA-Bw62 antigens were identified by isoelectric focusing, and sequencing studies revealed that these are a family of closely related alle...

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Veröffentlicht in:	Immunogenetics (New York) 1993, Vol.37 (2), p.108-113
Hauptverfasser:	YOON CHOO, S, LI-AN FAN, HANSEN, J. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Amino Acid Sequence Antigens Base Sequence binding Binding Sites Biological and medical sciences Bw62 determinant Cell Line DNA Fundamental and applied biological sciences. Psychology Fundamental immunology genetic variance histocompatibility antigen HLA Histocompatibility antigens (hla, h-2 and other systems) HLA-B Antigens - chemistry HLA-B Antigens - genetics HLA-B Antigens - immunology HLA-B15 Antigen Humans Isoelectric Focusing man Molecular immunology Molecular Sequence Data Phenotype Protein Structure, Tertiary sites T-Lymphocytes, Cytotoxic - immunology
Online-Zugang:	Volltext
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