Smaller Local Brain Volumes and Cerebral Atrophy in Spontaneously Hypertensive Rats

Spontaneously hypertensive rats (SHR) have enlarged cerebral ventricles from 8 weeks of age onward and smaller brains than age-matched, normotensive Wistar-Kyoto (WKY) rats (controls). At 6–7 months of age local cerebral glucose utilization is apparently lower in many brain areas of SHR relative to...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 1993-01, Vol.21 (1), p.105-111
Hauptverfasser:	Tajima, Atsushi, Hans, Franz-Josef, Livingstone, David, Wei, Ling, Finnegan, Wendy, De Maro, Joseph, Fenstermacher, Joseph
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arterial hypertension. Arterial hypotension Atrophy Biological and medical sciences Blood and lymphatic vessels Brain - pathology Cardiology. Vascular system Cerebral Ventricles - pathology Experimental diseases Hypertension - pathology Medical sciences Neurons - pathology Rats Rats, Inbred SHR Rats, Inbred WKY Sympathetic Nervous System - physiology
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