Relation of Glucose to α-Fetoprotein in Amniotic Fluid
A direct relationship between amniotic fluid glucose and α -fetoprotein (AFP) has been found between the 16th and 22nd weeks of pregnancy. This relationship is statistically significant (P
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Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 1981-03, Vol.57 (3), p.310-312 |
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container_title | Obstetrics and gynecology (New York. 1953) |
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creator | RULE, A H SLIOGERIS, V FARBER, M BRITTON, G VANDERVOORDE, J |
description | A direct relationship between amniotic fluid glucose and α -fetoprotein (AFP) has been found between the 16th and 22nd weeks of pregnancy. This relationship is statistically significant (P |
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This relationship is statistically significant (P<.001) in each of the 6 gestational weeks tested, and the coefficients of correlation vary from .74 to .91. The relationship between amniotic fluid AFP and another metabolite, urea nitrogen, was not significant (r=—.34), suggesting that the AFP-glucose relationship was not spurious. Absence of pregnancy-associated macroglobulins in the samples indicates that they were not contaminated by maternal serum. These data reflect an aspect of fetal metabolism or transport that should be investigated more thoroughly.</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>PMID: 6162139</identifier><language>eng</language><publisher>United States: The American College of Obstetricians and Gynecologists</publisher><subject>alpha-Fetoproteins - analysis ; Amniotic Fluid - analysis ; Blood Urea Nitrogen ; Female ; Glucose - analysis ; Humans ; Pregnancy ; Pregnancy Trimester, Third</subject><ispartof>Obstetrics and gynecology (New York. 1953), 1981-03, Vol.57 (3), p.310-312</ispartof><rights>1981 The American College of Obstetricians and Gynecologists</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6162139$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>RULE, A H</creatorcontrib><creatorcontrib>SLIOGERIS, V</creatorcontrib><creatorcontrib>FARBER, M</creatorcontrib><creatorcontrib>BRITTON, G</creatorcontrib><creatorcontrib>VANDERVOORDE, J</creatorcontrib><title>Relation of Glucose to α-Fetoprotein in Amniotic Fluid</title><title>Obstetrics and gynecology (New York. 1953)</title><addtitle>Obstet Gynecol</addtitle><description>A direct relationship between amniotic fluid glucose and α -fetoprotein (AFP) has been found between the 16th and 22nd weeks of pregnancy. This relationship is statistically significant (P<.001) in each of the 6 gestational weeks tested, and the coefficients of correlation vary from .74 to .91. The relationship between amniotic fluid AFP and another metabolite, urea nitrogen, was not significant (r=—.34), suggesting that the AFP-glucose relationship was not spurious. Absence of pregnancy-associated macroglobulins in the samples indicates that they were not contaminated by maternal serum. These data reflect an aspect of fetal metabolism or transport that should be investigated more thoroughly.</description><subject>alpha-Fetoproteins - analysis</subject><subject>Amniotic Fluid - analysis</subject><subject>Blood Urea Nitrogen</subject><subject>Female</subject><subject>Glucose - analysis</subject><subject>Humans</subject><subject>Pregnancy</subject><subject>Pregnancy Trimester, Third</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotUNtKAzEUDKLUWv0EYZ98C-S2uTyWYmuhIIiCb0s2FxrNbuomS_Gz_BG_yZUWDhzOzDCcmQswx1JQSCh9vwRzhIiCQjJ2DW5y_kAIYa7oDMw45gRTNQfixUVdQuqr5KtNHE3Kriqp-v2Ba1fSYUjFhb6aZtn1IZVgqnUcg70FV17H7O7OewHe1o-vqye4e95sV8sdPJAaCyipldYSzDxlhteWSSu0MZ5Ir5UkTBtZa99iabmRWDtGKOJta3zrhRGC0AV4OPlOn3yNLpemC9m4GHXv0pgbUddEKcYm4f1ZOLads81hCJ0evptz0olnJ_6YYnFD_ozj0Q3N3ulY9s3UDOKkRhAriRGdLvgPCfoHZ0VgMw</recordid><startdate>198103</startdate><enddate>198103</enddate><creator>RULE, A H</creator><creator>SLIOGERIS, V</creator><creator>FARBER, M</creator><creator>BRITTON, G</creator><creator>VANDERVOORDE, J</creator><general>The American College of Obstetricians and Gynecologists</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>198103</creationdate><title>Relation of Glucose to α-Fetoprotein in Amniotic Fluid</title><author>RULE, A H ; SLIOGERIS, V ; FARBER, M ; BRITTON, G ; VANDERVOORDE, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p2517-83d8dd214f34c65d48d7accf28fa9824ac85afb18d6c81ae42306bbcfbf7c7723</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>alpha-Fetoproteins - analysis</topic><topic>Amniotic Fluid - analysis</topic><topic>Blood Urea Nitrogen</topic><topic>Female</topic><topic>Glucose - analysis</topic><topic>Humans</topic><topic>Pregnancy</topic><topic>Pregnancy Trimester, Third</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>RULE, A H</creatorcontrib><creatorcontrib>SLIOGERIS, V</creatorcontrib><creatorcontrib>FARBER, M</creatorcontrib><creatorcontrib>BRITTON, G</creatorcontrib><creatorcontrib>VANDERVOORDE, J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>RULE, A H</au><au>SLIOGERIS, V</au><au>FARBER, M</au><au>BRITTON, G</au><au>VANDERVOORDE, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Relation of Glucose to α-Fetoprotein in Amniotic Fluid</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>1981-03</date><risdate>1981</risdate><volume>57</volume><issue>3</issue><spage>310</spage><epage>312</epage><pages>310-312</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><abstract>A direct relationship between amniotic fluid glucose and α -fetoprotein (AFP) has been found between the 16th and 22nd weeks of pregnancy. This relationship is statistically significant (P<.001) in each of the 6 gestational weeks tested, and the coefficients of correlation vary from .74 to .91. The relationship between amniotic fluid AFP and another metabolite, urea nitrogen, was not significant (r=—.34), suggesting that the AFP-glucose relationship was not spurious. Absence of pregnancy-associated macroglobulins in the samples indicates that they were not contaminated by maternal serum. These data reflect an aspect of fetal metabolism or transport that should be investigated more thoroughly.</abstract><cop>United States</cop><pub>The American College of Obstetricians and Gynecologists</pub><pmid>6162139</pmid><tpages>3</tpages></addata></record> |
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subjects | alpha-Fetoproteins - analysis Amniotic Fluid - analysis Blood Urea Nitrogen Female Glucose - analysis Humans Pregnancy Pregnancy Trimester, Third |
title | Relation of Glucose to α-Fetoprotein in Amniotic Fluid |
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