Erythrocyte transketolase activity and sudden infant death
Postmortem heart blood aspirates from 24 consecutive sudden infant deaths and 23 consecutive infant deaths from other causes yielded evidence of erythrocyte transketolase activity (ETKA) in every instance. ETKA measurements from cadaver specimens have not been previously reported. ETKA values did no...
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| Veröffentlicht in: | The American journal of clinical nutrition 1981-01, Vol.34 (1), p.65-67 |
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| container_title | The American journal of clinical nutrition |
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| creator | Peterson, D R Labbe, R F van Belle, G Chinn, N M |
| description | Postmortem heart blood aspirates from 24 consecutive sudden infant deaths and 23 consecutive infant deaths from other causes yielded evidence of erythrocyte transketolase activity (ETKA) in every instance. ETKA measurements from cadaver specimens have not been previously reported. ETKA values did not correlate with the interval from death to sampling or with age at death. Activity coefficients from postmortem material corresponded closely to those from previous studies on living subjects which suggests that the method of Bayoumi and Rosalki yields valid measurements at least for 77 h postmortem. Statistical comparisons of the sudden infant deaths with non-sudden infant deaths revealed no significant differences. This investigation failed to disclose evidence in favor of the hypothesis, advanced by Read, that unsuspected thiamin deficiency may explain some cases of the sudden infant death syndrome. |
| doi_str_mv | 10.1093/ajcn/34.1.65 |
| format | Article |
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ETKA measurements from cadaver specimens have not been previously reported. ETKA values did not correlate with the interval from death to sampling or with age at death. Activity coefficients from postmortem material corresponded closely to those from previous studies on living subjects which suggests that the method of Bayoumi and Rosalki yields valid measurements at least for 77 h postmortem. Statistical comparisons of the sudden infant deaths with non-sudden infant deaths revealed no significant differences. This investigation failed to disclose evidence in favor of the hypothesis, advanced by Read, that unsuspected thiamin deficiency may explain some cases of the sudden infant death syndrome.</description><identifier>ISSN: 0002-9165</identifier><identifier>DOI: 10.1093/ajcn/34.1.65</identifier><identifier>PMID: 7446460</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Erythrocytes - enzymology ; Humans ; Infant ; Infant, Newborn ; Sudden infant death ; Sudden Infant Death - blood ; Sudden Infant Death - etiology ; thiamin deficiency ; thiaminase ; Thiamine Deficiency - complications ; Transketolase - blood</subject><ispartof>The American journal of clinical nutrition, 1981-01, Vol.34 (1), p.65-67</ispartof><rights>1981 American Society for Nutrition.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c333t-202b1989d657614bea978ededbae791e225dd7270e7410181e21b2a477bf24673</citedby><cites>FETCH-LOGICAL-c333t-202b1989d657614bea978ededbae791e225dd7270e7410181e21b2a477bf24673</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7446460$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Peterson, D R</creatorcontrib><creatorcontrib>Labbe, R F</creatorcontrib><creatorcontrib>van Belle, G</creatorcontrib><creatorcontrib>Chinn, N M</creatorcontrib><title>Erythrocyte transketolase activity and sudden infant death</title><title>The American journal of clinical nutrition</title><addtitle>Am J Clin Nutr</addtitle><description>Postmortem heart blood aspirates from 24 consecutive sudden infant deaths and 23 consecutive infant deaths from other causes yielded evidence of erythrocyte transketolase activity (ETKA) in every instance. ETKA measurements from cadaver specimens have not been previously reported. ETKA values did not correlate with the interval from death to sampling or with age at death. Activity coefficients from postmortem material corresponded closely to those from previous studies on living subjects which suggests that the method of Bayoumi and Rosalki yields valid measurements at least for 77 h postmortem. Statistical comparisons of the sudden infant deaths with non-sudden infant deaths revealed no significant differences. This investigation failed to disclose evidence in favor of the hypothesis, advanced by Read, that unsuspected thiamin deficiency may explain some cases of the sudden infant death syndrome.</description><subject>Erythrocytes - enzymology</subject><subject>Humans</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Sudden infant death</subject><subject>Sudden Infant Death - blood</subject><subject>Sudden Infant Death - etiology</subject><subject>thiamin deficiency</subject><subject>thiaminase</subject><subject>Thiamine Deficiency - complications</subject><subject>Transketolase - blood</subject><issn>0002-9165</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1981</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkDtPwzAUhT2ASilsrEiZmEhrO34kbKgqD6kSC8yWY9-oLqlTbKdS_j2pWjExXemcT590D0J3BM8JroqF3hq_KNiczAW_QFOMMc0rIvgVuo5xizGhrBQTNJGMCSbwFD2twpA2oTNDgiwF7eM3pK7VETJtkju4NGTa2yz21oLPnG-0T5kFnTY36LLRbYTb852hr5fV5_ItX3-8vi-f17kpiiLlFNOaVGVlBZeCsBp0JUuwYGsNsiJAKbdWUolBMoJJOSakpppJWTeUCVnM0MPJuw_dTw8xqZ2LBtpWe-j6qCTnpCIcj-DjCTShizFAo_bB7XQYFMHqOI86zqMKpogSfMTvz96-3oH9g8_bjL049TA-d3AQVDQOvAHrApikbOf-F_8CZvd1UA</recordid><startdate>198101</startdate><enddate>198101</enddate><creator>Peterson, D R</creator><creator>Labbe, R F</creator><creator>van Belle, G</creator><creator>Chinn, N M</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198101</creationdate><title>Erythrocyte transketolase activity and sudden infant death</title><author>Peterson, D R ; Labbe, R F ; van Belle, G ; Chinn, N M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c333t-202b1989d657614bea978ededbae791e225dd7270e7410181e21b2a477bf24673</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1981</creationdate><topic>Erythrocytes - enzymology</topic><topic>Humans</topic><topic>Infant</topic><topic>Infant, Newborn</topic><topic>Sudden infant death</topic><topic>Sudden Infant Death - blood</topic><topic>Sudden Infant Death - etiology</topic><topic>thiamin deficiency</topic><topic>thiaminase</topic><topic>Thiamine Deficiency - complications</topic><topic>Transketolase - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Peterson, D R</creatorcontrib><creatorcontrib>Labbe, R F</creatorcontrib><creatorcontrib>van Belle, G</creatorcontrib><creatorcontrib>Chinn, N M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of clinical nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Peterson, D R</au><au>Labbe, R F</au><au>van Belle, G</au><au>Chinn, N M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Erythrocyte transketolase activity and sudden infant death</atitle><jtitle>The American journal of clinical nutrition</jtitle><addtitle>Am J Clin Nutr</addtitle><date>1981-01</date><risdate>1981</risdate><volume>34</volume><issue>1</issue><spage>65</spage><epage>67</epage><pages>65-67</pages><issn>0002-9165</issn><abstract>Postmortem heart blood aspirates from 24 consecutive sudden infant deaths and 23 consecutive infant deaths from other causes yielded evidence of erythrocyte transketolase activity (ETKA) in every instance. ETKA measurements from cadaver specimens have not been previously reported. ETKA values did not correlate with the interval from death to sampling or with age at death. Activity coefficients from postmortem material corresponded closely to those from previous studies on living subjects which suggests that the method of Bayoumi and Rosalki yields valid measurements at least for 77 h postmortem. Statistical comparisons of the sudden infant deaths with non-sudden infant deaths revealed no significant differences. This investigation failed to disclose evidence in favor of the hypothesis, advanced by Read, that unsuspected thiamin deficiency may explain some cases of the sudden infant death syndrome.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>7446460</pmid><doi>10.1093/ajcn/34.1.65</doi><tpages>3</tpages></addata></record> |
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| ispartof | The American journal of clinical nutrition, 1981-01, Vol.34 (1), p.65-67 |
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| language | eng |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Erythrocytes - enzymology Humans Infant Infant, Newborn Sudden infant death Sudden Infant Death - blood Sudden Infant Death - etiology thiamin deficiency thiaminase Thiamine Deficiency - complications Transketolase - blood |
| title | Erythrocyte transketolase activity and sudden infant death |
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