Efficacy and Safety of Therapeutic ERCP for the Elderly with Choledocholithiasis: Comparison with Younger Patients
Objective To clarify the efficacy and safety of therapeutic endoscopic retrograde cholangiopancreatography for the elderly with choledocholithiasis compared with younger patients. Methods Consecutive therapeutic ERCPs performed between 2005 and 2007 at our institution for 118 patients aged 80 years...
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| Veröffentlicht in: | Internal Medicine 2010, Vol.49(18), pp.1935-1941 |
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| container_issue | 18 |
| container_start_page | 1935 |
| container_title | Internal Medicine |
| container_volume | 49 |
| creator | Obana, Takashi Fujita, Naotaka Noda, Yutaka Kobayashi, Go Ito, Kei Horaguchi, Jun Koshita, Shinsuke Kanno, Yoshihide Yamashita, Yasunobu Kato, Yuhei Ogawa, Takahisa |
| description | Objective To clarify the efficacy and safety of therapeutic endoscopic retrograde cholangiopancreatography for the elderly with choledocholithiasis compared with younger patients. Methods Consecutive therapeutic ERCPs performed between 2005 and 2007 at our institution for 118 patients aged 80 years or older (group A) and 205 patients younger than 80 years old (group B) were retrospectively reviewed. Successful cannulation rate, complete stone clearance rate, complications and prognosis were compared between the two groups. Results Successful cannulation was achieved in 99.2% in group A versus 99.5% in group B. The complete stone clearance rate was significantly lower in group A than in group B (92.4% versus 99.0%, p |
| doi_str_mv | 10.2169/internalmedicine.49.3660 |
| format | Article |
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Methods Consecutive therapeutic ERCPs performed between 2005 and 2007 at our institution for 118 patients aged 80 years or older (group A) and 205 patients younger than 80 years old (group B) were retrospectively reviewed. Successful cannulation rate, complete stone clearance rate, complications and prognosis were compared between the two groups. Results Successful cannulation was achieved in 99.2% in group A versus 99.5% in group B. The complete stone clearance rate was significantly lower in group A than in group B (92.4% versus 99.0%, p<0.01). Plastic stent placement was performed for patients with incomplete duct clearance. There was no significant difference in the early complication rate between group A (5.5%) and group B (6.6%). Procedure-related mortality did not occur. Cholangitis-free survival was similar between the two groups. The short-term prognosis was comparable between those with complete duct clearance and those with biliary stent placement. Conclusion With a duct clearance rate of more than 90% and plastic stent placement for patients with poor general condition, therapeutic ERCP for choledocholithiasis in patients 80 years of age or older is comparable in safety and effectiveness to that in younger patients.</description><identifier>ISSN: 0918-2918</identifier><identifier>EISSN: 1349-7235</identifier><identifier>DOI: 10.2169/internalmedicine.49.3660</identifier><identifier>PMID: 20847495</identifier><language>eng</language><publisher>Japan: The Japanese Society of Internal Medicine</publisher><subject>Age Factors ; Aged ; Aged, 80 and over ; Cholangiopancreatography, Endoscopic Retrograde - adverse effects ; Cholangiopancreatography, Endoscopic Retrograde - instrumentation ; Cholangiopancreatography, Endoscopic Retrograde - methods ; choledocholithiasis ; Choledocholithiasis - diagnosis ; Choledocholithiasis - surgery ; elderly ; ERCP ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome</subject><ispartof>Internal Medicine, 2010, Vol.49(18), pp.1935-1941</ispartof><rights>2010 by The Japanese Society of Internal Medicine</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c526t-f01c25e65973323206a993c137ddbc0d013b30c971ed6ccbdf0094dca2510e3a3</citedby><cites>FETCH-LOGICAL-c526t-f01c25e65973323206a993c137ddbc0d013b30c971ed6ccbdf0094dca2510e3a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,1884,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20847495$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Obana, Takashi</creatorcontrib><creatorcontrib>Fujita, Naotaka</creatorcontrib><creatorcontrib>Noda, Yutaka</creatorcontrib><creatorcontrib>Kobayashi, Go</creatorcontrib><creatorcontrib>Ito, Kei</creatorcontrib><creatorcontrib>Horaguchi, Jun</creatorcontrib><creatorcontrib>Koshita, Shinsuke</creatorcontrib><creatorcontrib>Kanno, Yoshihide</creatorcontrib><creatorcontrib>Yamashita, Yasunobu</creatorcontrib><creatorcontrib>Kato, Yuhei</creatorcontrib><creatorcontrib>Ogawa, Takahisa</creatorcontrib><title>Efficacy and Safety of Therapeutic ERCP for the Elderly with Choledocholithiasis: Comparison with Younger Patients</title><title>Internal Medicine</title><addtitle>Intern. Med.</addtitle><description>Objective To clarify the efficacy and safety of therapeutic endoscopic retrograde cholangiopancreatography for the elderly with choledocholithiasis compared with younger patients. Methods Consecutive therapeutic ERCPs performed between 2005 and 2007 at our institution for 118 patients aged 80 years or older (group A) and 205 patients younger than 80 years old (group B) were retrospectively reviewed. Successful cannulation rate, complete stone clearance rate, complications and prognosis were compared between the two groups. Results Successful cannulation was achieved in 99.2% in group A versus 99.5% in group B. The complete stone clearance rate was significantly lower in group A than in group B (92.4% versus 99.0%, p<0.01). Plastic stent placement was performed for patients with incomplete duct clearance. There was no significant difference in the early complication rate between group A (5.5%) and group B (6.6%). Procedure-related mortality did not occur. Cholangitis-free survival was similar between the two groups. The short-term prognosis was comparable between those with complete duct clearance and those with biliary stent placement. Conclusion With a duct clearance rate of more than 90% and plastic stent placement for patients with poor general condition, therapeutic ERCP for choledocholithiasis in patients 80 years of age or older is comparable in safety and effectiveness to that in younger patients.</description><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cholangiopancreatography, Endoscopic Retrograde - adverse effects</subject><subject>Cholangiopancreatography, Endoscopic Retrograde - instrumentation</subject><subject>Cholangiopancreatography, Endoscopic Retrograde - methods</subject><subject>choledocholithiasis</subject><subject>Choledocholithiasis - diagnosis</subject><subject>Choledocholithiasis - surgery</subject><subject>elderly</subject><subject>ERCP</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Retrospective Studies</subject><subject>Treatment Outcome</subject><issn>0918-2918</issn><issn>1349-7235</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkE1rGzEQhkVJaJy0f6Ho1tM6-ljtrnori9sEAglNcshJyNIoq7CWHElL8b_vGrs-lF7mZZhnZuBBCFOyZLSR1z4USEGPG7De-ADLWi5505APaEF5LauWcXGGFkTSrmJzuUCXOb8RwrtWso_ogpGubmspFiitnPNGmx3WweJH7aDscHT4aYCktzAVb_DqV_-AXUy4DIBXo4U07vBvXwbcD3EEG80cc-t19vkb7uNmq5PPMRyglziFV0j4QRcPoeRP6NzpMcPnY16h5x-rp_6murv_edt_v6uMYE2pHKGGCWiEbDlnnJFGS8kN5a21a0MsoXzNiZEtBdsYs7aOEFlbo5mgBLjmV-jr4e42xfcJclEbnw2Mow4Qp6xaIWjXybqbye5AmhRzTuDUNvmNTjtFidoLV_8KV7VUe-Hz6pfjk2k9D0-Lfw3PwP0BeMtFv8IJ0GlWO8J_L9PuWKnk4kSaQScFgf8BmDCgcA</recordid><startdate>20100101</startdate><enddate>20100101</enddate><creator>Obana, Takashi</creator><creator>Fujita, Naotaka</creator><creator>Noda, Yutaka</creator><creator>Kobayashi, Go</creator><creator>Ito, Kei</creator><creator>Horaguchi, Jun</creator><creator>Koshita, Shinsuke</creator><creator>Kanno, Yoshihide</creator><creator>Yamashita, Yasunobu</creator><creator>Kato, Yuhei</creator><creator>Ogawa, Takahisa</creator><general>The Japanese Society of Internal Medicine</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20100101</creationdate><title>Efficacy and Safety of Therapeutic ERCP for the Elderly with Choledocholithiasis: Comparison with Younger Patients</title><author>Obana, Takashi ; Fujita, Naotaka ; Noda, Yutaka ; Kobayashi, Go ; Ito, Kei ; Horaguchi, Jun ; Koshita, Shinsuke ; Kanno, Yoshihide ; Yamashita, Yasunobu ; Kato, Yuhei ; Ogawa, Takahisa</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c526t-f01c25e65973323206a993c137ddbc0d013b30c971ed6ccbdf0094dca2510e3a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Cholangiopancreatography, Endoscopic Retrograde - adverse effects</topic><topic>Cholangiopancreatography, Endoscopic Retrograde - instrumentation</topic><topic>Cholangiopancreatography, Endoscopic Retrograde - methods</topic><topic>choledocholithiasis</topic><topic>Choledocholithiasis - diagnosis</topic><topic>Choledocholithiasis - surgery</topic><topic>elderly</topic><topic>ERCP</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Retrospective Studies</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Obana, Takashi</creatorcontrib><creatorcontrib>Fujita, Naotaka</creatorcontrib><creatorcontrib>Noda, Yutaka</creatorcontrib><creatorcontrib>Kobayashi, Go</creatorcontrib><creatorcontrib>Ito, Kei</creatorcontrib><creatorcontrib>Horaguchi, Jun</creatorcontrib><creatorcontrib>Koshita, Shinsuke</creatorcontrib><creatorcontrib>Kanno, Yoshihide</creatorcontrib><creatorcontrib>Yamashita, Yasunobu</creatorcontrib><creatorcontrib>Kato, Yuhei</creatorcontrib><creatorcontrib>Ogawa, Takahisa</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Internal Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Obana, Takashi</au><au>Fujita, Naotaka</au><au>Noda, Yutaka</au><au>Kobayashi, Go</au><au>Ito, Kei</au><au>Horaguchi, Jun</au><au>Koshita, Shinsuke</au><au>Kanno, Yoshihide</au><au>Yamashita, Yasunobu</au><au>Kato, Yuhei</au><au>Ogawa, Takahisa</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficacy and Safety of Therapeutic ERCP for the Elderly with Choledocholithiasis: Comparison with Younger Patients</atitle><jtitle>Internal Medicine</jtitle><addtitle>Intern. Med.</addtitle><date>2010-01-01</date><risdate>2010</risdate><volume>49</volume><issue>18</issue><spage>1935</spage><epage>1941</epage><pages>1935-1941</pages><issn>0918-2918</issn><eissn>1349-7235</eissn><abstract>Objective To clarify the efficacy and safety of therapeutic endoscopic retrograde cholangiopancreatography for the elderly with choledocholithiasis compared with younger patients. Methods Consecutive therapeutic ERCPs performed between 2005 and 2007 at our institution for 118 patients aged 80 years or older (group A) and 205 patients younger than 80 years old (group B) were retrospectively reviewed. Successful cannulation rate, complete stone clearance rate, complications and prognosis were compared between the two groups. Results Successful cannulation was achieved in 99.2% in group A versus 99.5% in group B. The complete stone clearance rate was significantly lower in group A than in group B (92.4% versus 99.0%, p<0.01). Plastic stent placement was performed for patients with incomplete duct clearance. There was no significant difference in the early complication rate between group A (5.5%) and group B (6.6%). Procedure-related mortality did not occur. Cholangitis-free survival was similar between the two groups. The short-term prognosis was comparable between those with complete duct clearance and those with biliary stent placement. Conclusion With a duct clearance rate of more than 90% and plastic stent placement for patients with poor general condition, therapeutic ERCP for choledocholithiasis in patients 80 years of age or older is comparable in safety and effectiveness to that in younger patients.</abstract><cop>Japan</cop><pub>The Japanese Society of Internal Medicine</pub><pmid>20847495</pmid><doi>10.2169/internalmedicine.49.3660</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Age Factors Aged Aged, 80 and over Cholangiopancreatography, Endoscopic Retrograde - adverse effects Cholangiopancreatography, Endoscopic Retrograde - instrumentation Cholangiopancreatography, Endoscopic Retrograde - methods choledocholithiasis Choledocholithiasis - diagnosis Choledocholithiasis - surgery elderly ERCP Female Follow-Up Studies Humans Male Middle Aged Retrospective Studies Treatment Outcome |
| title | Efficacy and Safety of Therapeutic ERCP for the Elderly with Choledocholithiasis: Comparison with Younger Patients |
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