Conventional endodontic treatment of primary molars using metronidazole as an intra-canal medicament: a pilot study
AIM: This was to evaluate the clinical and radiographic outcomes of an antibacterial drug (Metronidazole, Nidazol, IE Ulagay Ilac A.S) application as an intra-canal medicament combined with pulpectomy in infected primary molar teeth. METHODS: The study material consisted of data collected from child...
Gespeichert in:
| Veröffentlicht in: | European archives of paediatric dentistry 2010-08, Vol.11 (4), p.196-200 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 200 |
|---|---|
| container_issue | 4 |
| container_start_page | 196 |
| container_title | European archives of paediatric dentistry |
| container_volume | 11 |
| creator | Kargül, B. Tanboga, I. Altinok, B. |
| description | AIM:
This was to evaluate the clinical and radiographic outcomes of an antibacterial drug (Metronidazole, Nidazol, IE Ulagay Ilac A.S) application as an intra-canal medicament combined with pulpectomy in infected primary molar teeth.
METHODS:
The study material consisted of data collected from children treated at the Dental School Dept. of Paediatric Dentistry in Marmara University between 2000 and 2004. Clinical and radiographic data were collected over 2 years from patients who had received a topical application of metronidazole in root canal dressing before a pulpectomy was completed. Clinical success parameters were: no abscess formation, no fistula, no pain and no pathologic mobility at treated teeth with metranidazole dressing. The overall success and failure rates were analysed. Radiographic diagnosis was standardized between investigators and intra and inter-rater reliability assessed. Both investigators read and evaluated all radiographs, after a comparison of results, a consensus was agreed upon for each result.
STATISTICS
: All data were entered into an Excel format and SPSS 11.0 P < 0.05 were used for Windows and Chi-square for statistical analyses.
RESULTS
: There were 64 molars assessed for clinical and radiographic success. Considering the eruption times, success rate was 75% as determined by the last follow up clinically and radiographically according to predetermined success criteria. In the 64 molars, 4 cases demonstrated loss of the alveolar bone, 3 exhibited varying degrees of root resorptions on radiographic examination and 3 showed clinical pathologic mobility. Fistulae were observed in only 1 case and early loss was detected in 5 cases. C
ONCLUSION
: These results suggest that main factors responsible for failure may be associated with uncertain mixing proportions of the metronidazole paste and inadequate maxillary restorations. But some modifications in preparing the paste could increase its efficacy. |
| doi_str_mv | 10.1007/BF03262744 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_755183153</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2932478985</sourcerecordid><originalsourceid>FETCH-LOGICAL-c350t-fe2a7cf5404ed9ea5a846417947c3869f821dcaf005cf6d3a0442b7a3c5b7e5c3</originalsourceid><addsrcrecordid>eNptkcFKAzEQhoMotlYvPoAEPAjKarJJNllvWqwKghc9L9NstmzZTWqSFfTpTWlVEE-ZMB_fMP8gdEzJJSVEXt3OCMuLXHK-g8a0LIusVETsplpRlRWMkBE6CGFJiJBMFvtolBPFiWJ0jMLU2XdjY-ssdNjY2tUu_TSO3kDsUwe7Bq9824P_wL3rwAc8hNYucG-id7at4dN1BkPAYHFro4dMw1rWm7rVsFZcY8CrtnMRhzjUH4dor4EumKPtO0Gvs7uX6UP29Hz_OL15yjQTJGaNyUHqRnDCTV0aEKB4waksudRMFWWjclpraNJauilqBoTzfC6BaTGXRmg2QWcb78q7t8GEWPVt0KbrwBo3hEoKQVMIgiXy9A-5dINPS4QqL1nOpSqVSNT5htLeheBNU21zqSip1peofi-R4JOtcpinJH7Q7-gTcLEBQmrZhfG_M__RfQEwtJIX</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2932478985</pqid></control><display><type>article</type><title>Conventional endodontic treatment of primary molars using metronidazole as an intra-canal medicament: a pilot study</title><source>MEDLINE</source><source>SpringerLink (Online service)</source><source>ProQuest Central (Alumni)</source><source>ProQuest Central UK/Ireland</source><source>ProQuest Central</source><creator>Kargül, B. ; Tanboga, I. ; Altinok, B.</creator><creatorcontrib>Kargül, B. ; Tanboga, I. ; Altinok, B.</creatorcontrib><description>AIM:
This was to evaluate the clinical and radiographic outcomes of an antibacterial drug (Metronidazole, Nidazol, IE Ulagay Ilac A.S) application as an intra-canal medicament combined with pulpectomy in infected primary molar teeth.
METHODS:
The study material consisted of data collected from children treated at the Dental School Dept. of Paediatric Dentistry in Marmara University between 2000 and 2004. Clinical and radiographic data were collected over 2 years from patients who had received a topical application of metronidazole in root canal dressing before a pulpectomy was completed. Clinical success parameters were: no abscess formation, no fistula, no pain and no pathologic mobility at treated teeth with metranidazole dressing. The overall success and failure rates were analysed. Radiographic diagnosis was standardized between investigators and intra and inter-rater reliability assessed. Both investigators read and evaluated all radiographs, after a comparison of results, a consensus was agreed upon for each result.
STATISTICS
: All data were entered into an Excel format and SPSS 11.0 P < 0.05 were used for Windows and Chi-square for statistical analyses.
RESULTS
: There were 64 molars assessed for clinical and radiographic success. Considering the eruption times, success rate was 75% as determined by the last follow up clinically and radiographically according to predetermined success criteria. In the 64 molars, 4 cases demonstrated loss of the alveolar bone, 3 exhibited varying degrees of root resorptions on radiographic examination and 3 showed clinical pathologic mobility. Fistulae were observed in only 1 case and early loss was detected in 5 cases. C
ONCLUSION
: These results suggest that main factors responsible for failure may be associated with uncertain mixing proportions of the metronidazole paste and inadequate maxillary restorations. But some modifications in preparing the paste could increase its efficacy.</description><identifier>ISSN: 1818-6300</identifier><identifier>EISSN: 1996-9805</identifier><identifier>DOI: 10.1007/BF03262744</identifier><identifier>PMID: 20840831</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Abscess - etiology ; Alveolar Bone Loss - etiology ; Anti-Infective Agents - therapeutic use ; Chi-square test ; Child ; Dental Fistula - etiology ; Dental Pulp Diseases - therapy ; Dentistry ; Evaluation ; Failure rates ; Female ; Follow-Up Studies ; Humans ; Male ; Medicine ; Metronidazole - therapeutic use ; Molar - diagnostic imaging ; Molar - pathology ; Pain Measurement ; Pilot Projects ; Pulpectomy - methods ; Radiography, Bitewing ; Reliability analysis ; Retrospective Studies ; Root Canal Irrigants - therapeutic use ; Root Canal Obturation - methods ; Root Canal Therapy - methods ; Root Resorption - etiology ; Statistical analysis ; Success ; Tooth Mobility - etiology ; Tooth, Deciduous - diagnostic imaging ; Tooth, Deciduous - pathology ; Tooth, Nonvital - therapy ; Treatment Outcome</subject><ispartof>European archives of paediatric dentistry, 2010-08, Vol.11 (4), p.196-200</ispartof><rights>Adis International 2010</rights><rights>Adis International 2010.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c350t-fe2a7cf5404ed9ea5a846417947c3869f821dcaf005cf6d3a0442b7a3c5b7e5c3</citedby><cites>FETCH-LOGICAL-c350t-fe2a7cf5404ed9ea5a846417947c3869f821dcaf005cf6d3a0442b7a3c5b7e5c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/BF03262744$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2932478985?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,21388,21389,27924,27925,33530,33531,33744,33745,41488,42557,43659,43805,51319,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20840831$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kargül, B.</creatorcontrib><creatorcontrib>Tanboga, I.</creatorcontrib><creatorcontrib>Altinok, B.</creatorcontrib><title>Conventional endodontic treatment of primary molars using metronidazole as an intra-canal medicament: a pilot study</title><title>European archives of paediatric dentistry</title><addtitle>Eur Arch Paediatr Dent</addtitle><addtitle>Eur Arch Paediatr Dent</addtitle><description>AIM:
This was to evaluate the clinical and radiographic outcomes of an antibacterial drug (Metronidazole, Nidazol, IE Ulagay Ilac A.S) application as an intra-canal medicament combined with pulpectomy in infected primary molar teeth.
METHODS:
The study material consisted of data collected from children treated at the Dental School Dept. of Paediatric Dentistry in Marmara University between 2000 and 2004. Clinical and radiographic data were collected over 2 years from patients who had received a topical application of metronidazole in root canal dressing before a pulpectomy was completed. Clinical success parameters were: no abscess formation, no fistula, no pain and no pathologic mobility at treated teeth with metranidazole dressing. The overall success and failure rates were analysed. Radiographic diagnosis was standardized between investigators and intra and inter-rater reliability assessed. Both investigators read and evaluated all radiographs, after a comparison of results, a consensus was agreed upon for each result.
STATISTICS
: All data were entered into an Excel format and SPSS 11.0 P < 0.05 were used for Windows and Chi-square for statistical analyses.
RESULTS
: There were 64 molars assessed for clinical and radiographic success. Considering the eruption times, success rate was 75% as determined by the last follow up clinically and radiographically according to predetermined success criteria. In the 64 molars, 4 cases demonstrated loss of the alveolar bone, 3 exhibited varying degrees of root resorptions on radiographic examination and 3 showed clinical pathologic mobility. Fistulae were observed in only 1 case and early loss was detected in 5 cases. C
ONCLUSION
: These results suggest that main factors responsible for failure may be associated with uncertain mixing proportions of the metronidazole paste and inadequate maxillary restorations. But some modifications in preparing the paste could increase its efficacy.</description><subject>Abscess - etiology</subject><subject>Alveolar Bone Loss - etiology</subject><subject>Anti-Infective Agents - therapeutic use</subject><subject>Chi-square test</subject><subject>Child</subject><subject>Dental Fistula - etiology</subject><subject>Dental Pulp Diseases - therapy</subject><subject>Dentistry</subject><subject>Evaluation</subject><subject>Failure rates</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Metronidazole - therapeutic use</subject><subject>Molar - diagnostic imaging</subject><subject>Molar - pathology</subject><subject>Pain Measurement</subject><subject>Pilot Projects</subject><subject>Pulpectomy - methods</subject><subject>Radiography, Bitewing</subject><subject>Reliability analysis</subject><subject>Retrospective Studies</subject><subject>Root Canal Irrigants - therapeutic use</subject><subject>Root Canal Obturation - methods</subject><subject>Root Canal Therapy - methods</subject><subject>Root Resorption - etiology</subject><subject>Statistical analysis</subject><subject>Success</subject><subject>Tooth Mobility - etiology</subject><subject>Tooth, Deciduous - diagnostic imaging</subject><subject>Tooth, Deciduous - pathology</subject><subject>Tooth, Nonvital - therapy</subject><subject>Treatment Outcome</subject><issn>1818-6300</issn><issn>1996-9805</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNptkcFKAzEQhoMotlYvPoAEPAjKarJJNllvWqwKghc9L9NstmzZTWqSFfTpTWlVEE-ZMB_fMP8gdEzJJSVEXt3OCMuLXHK-g8a0LIusVETsplpRlRWMkBE6CGFJiJBMFvtolBPFiWJ0jMLU2XdjY-ssdNjY2tUu_TSO3kDsUwe7Bq9824P_wL3rwAc8hNYucG-id7at4dN1BkPAYHFro4dMw1rWm7rVsFZcY8CrtnMRhzjUH4dor4EumKPtO0Gvs7uX6UP29Hz_OL15yjQTJGaNyUHqRnDCTV0aEKB4waksudRMFWWjclpraNJauilqBoTzfC6BaTGXRmg2QWcb78q7t8GEWPVt0KbrwBo3hEoKQVMIgiXy9A-5dINPS4QqL1nOpSqVSNT5htLeheBNU21zqSip1peofi-R4JOtcpinJH7Q7-gTcLEBQmrZhfG_M__RfQEwtJIX</recordid><startdate>20100801</startdate><enddate>20100801</enddate><creator>Kargül, B.</creator><creator>Tanboga, I.</creator><creator>Altinok, B.</creator><general>Springer-Verlag</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FE</scope><scope>8FG</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>D1I</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB.</scope><scope>M0S</scope><scope>PDBOC</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20100801</creationdate><title>Conventional endodontic treatment of primary molars using metronidazole as an intra-canal medicament: a pilot study</title><author>Kargül, B. ; Tanboga, I. ; Altinok, B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c350t-fe2a7cf5404ed9ea5a846417947c3869f821dcaf005cf6d3a0442b7a3c5b7e5c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Abscess - etiology</topic><topic>Alveolar Bone Loss - etiology</topic><topic>Anti-Infective Agents - therapeutic use</topic><topic>Chi-square test</topic><topic>Child</topic><topic>Dental Fistula - etiology</topic><topic>Dental Pulp Diseases - therapy</topic><topic>Dentistry</topic><topic>Evaluation</topic><topic>Failure rates</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Metronidazole - therapeutic use</topic><topic>Molar - diagnostic imaging</topic><topic>Molar - pathology</topic><topic>Pain Measurement</topic><topic>Pilot Projects</topic><topic>Pulpectomy - methods</topic><topic>Radiography, Bitewing</topic><topic>Reliability analysis</topic><topic>Retrospective Studies</topic><topic>Root Canal Irrigants - therapeutic use</topic><topic>Root Canal Obturation - methods</topic><topic>Root Canal Therapy - methods</topic><topic>Root Resorption - etiology</topic><topic>Statistical analysis</topic><topic>Success</topic><topic>Tooth Mobility - etiology</topic><topic>Tooth, Deciduous - diagnostic imaging</topic><topic>Tooth, Deciduous - pathology</topic><topic>Tooth, Nonvital - therapy</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kargül, B.</creatorcontrib><creatorcontrib>Tanboga, I.</creatorcontrib><creatorcontrib>Altinok, B.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>https://resources.nclive.org/materials</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Materials science collection</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>European archives of paediatric dentistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kargül, B.</au><au>Tanboga, I.</au><au>Altinok, B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Conventional endodontic treatment of primary molars using metronidazole as an intra-canal medicament: a pilot study</atitle><jtitle>European archives of paediatric dentistry</jtitle><stitle>Eur Arch Paediatr Dent</stitle><addtitle>Eur Arch Paediatr Dent</addtitle><date>2010-08-01</date><risdate>2010</risdate><volume>11</volume><issue>4</issue><spage>196</spage><epage>200</epage><pages>196-200</pages><issn>1818-6300</issn><eissn>1996-9805</eissn><abstract>AIM:
This was to evaluate the clinical and radiographic outcomes of an antibacterial drug (Metronidazole, Nidazol, IE Ulagay Ilac A.S) application as an intra-canal medicament combined with pulpectomy in infected primary molar teeth.
METHODS:
The study material consisted of data collected from children treated at the Dental School Dept. of Paediatric Dentistry in Marmara University between 2000 and 2004. Clinical and radiographic data were collected over 2 years from patients who had received a topical application of metronidazole in root canal dressing before a pulpectomy was completed. Clinical success parameters were: no abscess formation, no fistula, no pain and no pathologic mobility at treated teeth with metranidazole dressing. The overall success and failure rates were analysed. Radiographic diagnosis was standardized between investigators and intra and inter-rater reliability assessed. Both investigators read and evaluated all radiographs, after a comparison of results, a consensus was agreed upon for each result.
STATISTICS
: All data were entered into an Excel format and SPSS 11.0 P < 0.05 were used for Windows and Chi-square for statistical analyses.
RESULTS
: There were 64 molars assessed for clinical and radiographic success. Considering the eruption times, success rate was 75% as determined by the last follow up clinically and radiographically according to predetermined success criteria. In the 64 molars, 4 cases demonstrated loss of the alveolar bone, 3 exhibited varying degrees of root resorptions on radiographic examination and 3 showed clinical pathologic mobility. Fistulae were observed in only 1 case and early loss was detected in 5 cases. C
ONCLUSION
: These results suggest that main factors responsible for failure may be associated with uncertain mixing proportions of the metronidazole paste and inadequate maxillary restorations. But some modifications in preparing the paste could increase its efficacy.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>20840831</pmid><doi>10.1007/BF03262744</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1818-6300 |
| ispartof | European archives of paediatric dentistry, 2010-08, Vol.11 (4), p.196-200 |
| issn | 1818-6300 1996-9805 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_755183153 |
| source | MEDLINE; SpringerLink (Online service); ProQuest Central (Alumni); ProQuest Central UK/Ireland; ProQuest Central |
| subjects | Abscess - etiology Alveolar Bone Loss - etiology Anti-Infective Agents - therapeutic use Chi-square test Child Dental Fistula - etiology Dental Pulp Diseases - therapy Dentistry Evaluation Failure rates Female Follow-Up Studies Humans Male Medicine Metronidazole - therapeutic use Molar - diagnostic imaging Molar - pathology Pain Measurement Pilot Projects Pulpectomy - methods Radiography, Bitewing Reliability analysis Retrospective Studies Root Canal Irrigants - therapeutic use Root Canal Obturation - methods Root Canal Therapy - methods Root Resorption - etiology Statistical analysis Success Tooth Mobility - etiology Tooth, Deciduous - diagnostic imaging Tooth, Deciduous - pathology Tooth, Nonvital - therapy Treatment Outcome |
| title | Conventional endodontic treatment of primary molars using metronidazole as an intra-canal medicament: a pilot study |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T06%3A16%3A20IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Conventional%20endodontic%20treatment%20of%20primary%20molars%20using%20metronidazole%20as%20an%20intra-canal%20medicament:%20a%20pilot%20study&rft.jtitle=European%20archives%20of%20paediatric%20dentistry&rft.au=Karg%C3%BCl,%20B.&rft.date=2010-08-01&rft.volume=11&rft.issue=4&rft.spage=196&rft.epage=200&rft.pages=196-200&rft.issn=1818-6300&rft.eissn=1996-9805&rft_id=info:doi/10.1007/BF03262744&rft_dat=%3Cproquest_cross%3E2932478985%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2932478985&rft_id=info:pmid/20840831&rfr_iscdi=true |