Electrocardiographic changes during continuous intravenous application of bupivacaine in neonatal pigs

It is controversial as to whether T-wave elevation is caused by local anaesthetics, epinephrine, or their combination. It has been shown that T-elevation after intravascular injection of a small bupivacaine test dose is caused by epinephrine and not by bupivacaine. The aim of this study was to inves...

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Veröffentlicht in:	British journal of anaesthesia : BJA 2010-10, Vol.105 (4), p.437-441
Hauptverfasser:	Mauch, J, Kutter, A.P.N., Madjdpour, C, Spielmann, N, Balmer, C, Frotzler, A, Bettschart-Wolfensberger, R, Weiss, M
Format:	Artikel
Sprache:	eng
Schlagworte:	anaesthetics local anaesthetics local, bupivacaine Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anesthetics, Local - administration & dosage Anesthetics, Local - pharmacology Animals Animals, Newborn Biological and medical sciences bupivacaine Bupivacaine - administration & dosage Bupivacaine - pharmacology conduction Dose-Response Relationship, Drug Electrocardiography - drug effects Female heart heart rate Heart Rate - drug effects heart, conduction heart, heart rate Infusions, Intravenous local anaesthetics Male Medical sciences Sus scrofa toxicity toxicity, local anaesthetics
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