Repin1 maybe involved in the regulation of cell size and glucose transport in adipocytes

► First notion that Repin1 regulates genes associated with lipid droplet size. ► siRNA based knockdown of Repin1 in 3T3-L1 cells causes smaller adipocyte size. ► Repin1 KO alters glucose transport into 3T3-L1 cells. ► Repin1 KO significantly changes GLUT1, GLUT4 mRNA expression in vitro. ► Human Rep...

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Veröffentlicht in:	Biochemical and biophysical research communications 2010-09, Vol.400 (2), p.246-251
Hauptverfasser:	Ruschke, Karen, Illes, Monica, Kern, Matthias, Klöting, Ingrid, Fasshauer, Mathias, Schön, Michael R., Kosacka, Joanna, Fitzl, Günther, Kovacs, Peter, Stumvoll, Michael, Blüher, Matthias, Klöting, Nora
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3-L1 Cells Adipocytes - cytology Adipocytes - drug effects Adipocytes - metabolism Adipogenesis Adipogenesis - genetics Adipose Tissue - metabolism Animals Basic Helix-Loop-Helix Leucine Zipper Transcription Factors Cell Size DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Down-Regulation Female Gene Expression Regulation Gene Knockdown Techniques Glucose - metabolism Glucose Transporter Type 1 - genetics Glucose Transporter Type 4 - genetics Glucose uptake Humans Insulin - pharmacology Lipid droplet size Lipid Metabolism - genetics Male Mice Obesity Repin1
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