High Level of Plasma Endothelin-1 Predicts Development of Hypertension in Normotensive Subjects

Background Endothelin-1 (ET-1) is a potent vasoconstrictor derived from the endothelium. However, most large scale cross-sectional studies in humans have indicated no relationship between plasma ET-1 levels and hypertension. The present study was designed to determine whether high plasma ET-1 levels...

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Veröffentlicht in:	American journal of hypertension 2010-10, Vol.23 (10), p.1103-1107
Hauptverfasser:	Kumagae, Shun-ichi, Adachi, Hisashi, Jacobs, David R., Hirai, Yuji, Enomoto, Mika, Fukami, Ako, Otsuka, Maki, Nanjo, Yasuki, Esaki, Eishi, Kumagai, Eita, Yoshikawa, Kuniko, Yokoi, Kanako, Ogata, Kinuka, Tsukagawa, Eri, Kasahara, Akiko, Murayama, Kyoko, Imaizumi, Tsutomu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Arterial hypertension. Arterial hypotension Biological and medical sciences Blood and lymphatic vessels blood pressure Blood Pressure - physiology Cardiology. Vascular system Clinical manifestations. Epidemiology. Investigative techniques. Etiology Cohort Studies Cross-Sectional Studies Endothelin-1 - blood endothelium epidemiology Female Humans hypertension Hypertension - blood Hypertension - epidemiology Japan - epidemiology Longitudinal Studies Male Medical sciences Middle Aged Odds Ratio Predictive Value of Tests prospective study Risk Factors Seven Countries Study Tanushimaru
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