Prophylactic use of aspirin does not induce anaemia among adults
Summary Background: Aspirin is considered one of the most prescribed drugs worldwide, predominantly for its cardioprotective effects. However, its use may be precluded by gastrointestinal and haematological side‐effects. Objective: To investigate the association between the prophylactic use of asp...
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Veröffentlicht in: | Journal of clinical pharmacy and therapeutics 2010-08, Vol.35 (4), p.415-419 |
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creator | Al-Azzam, S. I. AlMahasneh, F. Mhaidat, N. Alzoubi, K. H. Khader, Y. S. |
description | Summary
Background: Aspirin is considered one of the most prescribed drugs worldwide, predominantly for its cardioprotective effects. However, its use may be precluded by gastrointestinal and haematological side‐effects.
Objective: To investigate the association between the prophylactic use of aspirin and the prevalence of anaemia among adults. Other demographic factors and co‐morbid conditions such as kidney or liver failure, diabetes mellitus, hypertension, hyperlipidemia, coronary artery disease, ulcer, ulcer medications, and the use of non‐steroidal anti‐inflammatory drugs, which might be associated with anaemia, were also investigated.
Results: No association between aspirin use and prevalence of anaemia was observed. Age and smoking were the only factors contributing significantly to the occurrence of anaemia. Moreover, gender, age and the use of peptic ulcer medication were associated with reduced haemoglobin levels.
Conclusion: The results may help in minimizing concerns about the development of anaemia among patients on aspirin. They highlight the importance of age, gender, smoking and ulcer medication in determining the incidence of anaemia among those patients. |
doi_str_mv | 10.1111/j.1365-2710.2009.01113.x |
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Background: Aspirin is considered one of the most prescribed drugs worldwide, predominantly for its cardioprotective effects. However, its use may be precluded by gastrointestinal and haematological side‐effects.
Objective: To investigate the association between the prophylactic use of aspirin and the prevalence of anaemia among adults. Other demographic factors and co‐morbid conditions such as kidney or liver failure, diabetes mellitus, hypertension, hyperlipidemia, coronary artery disease, ulcer, ulcer medications, and the use of non‐steroidal anti‐inflammatory drugs, which might be associated with anaemia, were also investigated.
Results: No association between aspirin use and prevalence of anaemia was observed. Age and smoking were the only factors contributing significantly to the occurrence of anaemia. Moreover, gender, age and the use of peptic ulcer medication were associated with reduced haemoglobin levels.
Conclusion: The results may help in minimizing concerns about the development of anaemia among patients on aspirin. They highlight the importance of age, gender, smoking and ulcer medication in determining the incidence of anaemia among those patients.</description><identifier>ISSN: 0269-4727</identifier><identifier>EISSN: 1365-2710</identifier><identifier>DOI: 10.1111/j.1365-2710.2009.01113.x</identifier><identifier>PMID: 20853549</identifier><identifier>CODEN: JCPTED</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adult ; Age Factors ; Aged ; Aged, 80 and over ; anaemia ; Anemia - chemically induced ; Anemia - epidemiology ; Anemias. Hemoglobinopathies ; Anti-Inflammatory Agents, Non-Steroidal - adverse effects ; Anti-Inflammatory Agents, Non-Steroidal - therapeutic use ; aspirin ; Aspirin - adverse effects ; Aspirin - therapeutic use ; Biological and medical sciences ; Cardiotonic Agents - adverse effects ; Cardiotonic Agents - therapeutic use ; Cardiovascular Diseases - prevention & control ; deficiency ; Diseases of red blood cells ; Female ; Hematologic and hematopoietic diseases ; Hemoglobins - analysis ; Humans ; Male ; Medical sciences ; Middle Aged ; Pharmacology. Drug treatments ; Prevalence ; prophylaxis ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Sex Factors ; Smoking</subject><ispartof>Journal of clinical pharmacy and therapeutics, 2010-08, Vol.35 (4), p.415-419</ispartof><rights>2010 The Authors. Journal compilation © 2010 Blackwell Publishing Ltd</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c4933-d9cb35115c22f7a318e5f74cdba1e91206be2303cb9ceed3ca704cd62bb678393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-2710.2009.01113.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-2710.2009.01113.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=22980511$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20853549$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Al-Azzam, S. I.</creatorcontrib><creatorcontrib>AlMahasneh, F.</creatorcontrib><creatorcontrib>Mhaidat, N.</creatorcontrib><creatorcontrib>Alzoubi, K. H.</creatorcontrib><creatorcontrib>Khader, Y. S.</creatorcontrib><title>Prophylactic use of aspirin does not induce anaemia among adults</title><title>Journal of clinical pharmacy and therapeutics</title><addtitle>J Clin Pharm Ther</addtitle><description>Summary
Background: Aspirin is considered one of the most prescribed drugs worldwide, predominantly for its cardioprotective effects. However, its use may be precluded by gastrointestinal and haematological side‐effects.
Objective: To investigate the association between the prophylactic use of aspirin and the prevalence of anaemia among adults. Other demographic factors and co‐morbid conditions such as kidney or liver failure, diabetes mellitus, hypertension, hyperlipidemia, coronary artery disease, ulcer, ulcer medications, and the use of non‐steroidal anti‐inflammatory drugs, which might be associated with anaemia, were also investigated.
Results: No association between aspirin use and prevalence of anaemia was observed. Age and smoking were the only factors contributing significantly to the occurrence of anaemia. Moreover, gender, age and the use of peptic ulcer medication were associated with reduced haemoglobin levels.
Conclusion: The results may help in minimizing concerns about the development of anaemia among patients on aspirin. They highlight the importance of age, gender, smoking and ulcer medication in determining the incidence of anaemia among those patients.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>anaemia</subject><subject>Anemia - chemically induced</subject><subject>Anemia - epidemiology</subject><subject>Anemias. Hemoglobinopathies</subject><subject>Anti-Inflammatory Agents, Non-Steroidal - adverse effects</subject><subject>Anti-Inflammatory Agents, Non-Steroidal - therapeutic use</subject><subject>aspirin</subject><subject>Aspirin - adverse effects</subject><subject>Aspirin - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Cardiotonic Agents - adverse effects</subject><subject>Cardiotonic Agents - therapeutic use</subject><subject>Cardiovascular Diseases - prevention & control</subject><subject>deficiency</subject><subject>Diseases of red blood cells</subject><subject>Female</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Hemoglobins - analysis</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pharmacology. Drug treatments</subject><subject>Prevalence</subject><subject>prophylaxis</subject><subject>Retrospective Studies</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Sex Factors</subject><subject>Smoking</subject><issn>0269-4727</issn><issn>1365-2710</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkVGPEyEQx4nReLX6FQyJMfqyPWAKLC9G0-jdmYvexVMTXwjLskrdXSrsxvbby9peTXww8gKZ-c1_mPkjhClZ0HxO1wsKghdM5gAjRC1IjsJiewfNjom7aEaYUMVSMnmCHqS0JoQIyeA-OmGk5MCXaoZeXsWw-bZrjR28xWNyODTYpI2Pvsd1cAn3YcC-r0frsOmN67zBpgv9V2zqsR3SQ3SvMW1yjw73HH188_pmdV5cvj-7WL26LOxSARS1shVwSrllrJEGaOl4I5e2rgx1ijIiKseAgK2Uda4GayTJWcGqSsgSFMzRs73uJoYfo0uD7nyyrm1N78KYtOSccpXnzuTzf5K0lKwEAVl2jp78ha7DGPs8R6aE4FAKzjJV7ikbQ0rRNXoTfWfiTlOiJz_0Wk9r19Pa9eSH_u2H3ubSx4cGY9W5-lh4a0AGnh4Ak6xpm2h669MfjqmS5LVl7sWe--lbt_vvD-i3q6ub6ZkFir2AT4PbHgVM_K6FBMn153dnuZ6RD1-ur_Un-AWWCLNR</recordid><startdate>201008</startdate><enddate>201008</enddate><creator>Al-Azzam, S. I.</creator><creator>AlMahasneh, F.</creator><creator>Mhaidat, N.</creator><creator>Alzoubi, K. H.</creator><creator>Khader, Y. S.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><general>Hindawi Limited</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TM</scope><scope>7TO</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>7X8</scope></search><sort><creationdate>201008</creationdate><title>Prophylactic use of aspirin does not induce anaemia among adults</title><author>Al-Azzam, S. I. ; AlMahasneh, F. ; Mhaidat, N. ; Alzoubi, K. H. ; Khader, Y. S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4933-d9cb35115c22f7a318e5f74cdba1e91206be2303cb9ceed3ca704cd62bb678393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>anaemia</topic><topic>Anemia - chemically induced</topic><topic>Anemia - epidemiology</topic><topic>Anemias. Hemoglobinopathies</topic><topic>Anti-Inflammatory Agents, Non-Steroidal - adverse effects</topic><topic>Anti-Inflammatory Agents, Non-Steroidal - therapeutic use</topic><topic>aspirin</topic><topic>Aspirin - adverse effects</topic><topic>Aspirin - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Cardiotonic Agents - adverse effects</topic><topic>Cardiotonic Agents - therapeutic use</topic><topic>Cardiovascular Diseases - prevention & control</topic><topic>deficiency</topic><topic>Diseases of red blood cells</topic><topic>Female</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Hemoglobins - analysis</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pharmacology. Drug treatments</topic><topic>Prevalence</topic><topic>prophylaxis</topic><topic>Retrospective Studies</topic><topic>Risk Assessment</topic><topic>Risk Factors</topic><topic>Sex Factors</topic><topic>Smoking</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Al-Azzam, S. I.</creatorcontrib><creatorcontrib>AlMahasneh, F.</creatorcontrib><creatorcontrib>Mhaidat, N.</creatorcontrib><creatorcontrib>Alzoubi, K. H.</creatorcontrib><creatorcontrib>Khader, Y. S.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical pharmacy and therapeutics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Al-Azzam, S. I.</au><au>AlMahasneh, F.</au><au>Mhaidat, N.</au><au>Alzoubi, K. H.</au><au>Khader, Y. S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prophylactic use of aspirin does not induce anaemia among adults</atitle><jtitle>Journal of clinical pharmacy and therapeutics</jtitle><addtitle>J Clin Pharm Ther</addtitle><date>2010-08</date><risdate>2010</risdate><volume>35</volume><issue>4</issue><spage>415</spage><epage>419</epage><pages>415-419</pages><issn>0269-4727</issn><eissn>1365-2710</eissn><coden>JCPTED</coden><abstract>Summary
Background: Aspirin is considered one of the most prescribed drugs worldwide, predominantly for its cardioprotective effects. However, its use may be precluded by gastrointestinal and haematological side‐effects.
Objective: To investigate the association between the prophylactic use of aspirin and the prevalence of anaemia among adults. Other demographic factors and co‐morbid conditions such as kidney or liver failure, diabetes mellitus, hypertension, hyperlipidemia, coronary artery disease, ulcer, ulcer medications, and the use of non‐steroidal anti‐inflammatory drugs, which might be associated with anaemia, were also investigated.
Results: No association between aspirin use and prevalence of anaemia was observed. Age and smoking were the only factors contributing significantly to the occurrence of anaemia. Moreover, gender, age and the use of peptic ulcer medication were associated with reduced haemoglobin levels.
Conclusion: The results may help in minimizing concerns about the development of anaemia among patients on aspirin. They highlight the importance of age, gender, smoking and ulcer medication in determining the incidence of anaemia among those patients.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>20853549</pmid><doi>10.1111/j.1365-2710.2009.01113.x</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Age Factors Aged Aged, 80 and over anaemia Anemia - chemically induced Anemia - epidemiology Anemias. Hemoglobinopathies Anti-Inflammatory Agents, Non-Steroidal - adverse effects Anti-Inflammatory Agents, Non-Steroidal - therapeutic use aspirin Aspirin - adverse effects Aspirin - therapeutic use Biological and medical sciences Cardiotonic Agents - adverse effects Cardiotonic Agents - therapeutic use Cardiovascular Diseases - prevention & control deficiency Diseases of red blood cells Female Hematologic and hematopoietic diseases Hemoglobins - analysis Humans Male Medical sciences Middle Aged Pharmacology. Drug treatments Prevalence prophylaxis Retrospective Studies Risk Assessment Risk Factors Sex Factors Smoking |
title | Prophylactic use of aspirin does not induce anaemia among adults |
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