Evaluation of immunocompetence and nutritional status in patients with bulimia nervosa
Nutritional status of patients suffering from bulimia nervosa was evaluated by anthropometric, hematological, and immunological parameters in comparison with a healthy control group. Anthropometry showed no signs of malnutrition in either group. Bulimic patients showed a significant decrease in most...
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| Veröffentlicht in: | The American journal of clinical nutrition 1993-01, Vol.57 (1), p.65-69 |
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| creator | Marcos, A Varela, P Santacruz, I Muñoz-Vélez, A |
| description | Nutritional status of patients suffering from bulimia nervosa was evaluated by anthropometric, hematological, and immunological parameters in comparison with a healthy control group. Anthropometry showed no signs of malnutrition in either group. Bulimic patients showed a significant decrease in most of the routine clinical indexes related to red blood cells. Lymphocyte subsets CD2 and CD4 in bulimic patients were lower than in controls, whereas CD8 remained unmodified, leading to a lower CD4:CD8 in bulimic patients. The decreases in CD2 and CD4 numbers might be linked to an impaired cell-mediated immune function, as evaluated by the response to skin tests. The B lymphocyte subset was increased in the bulimic group. Innate immunity was impaired in the bulimic patients. Although anthropometric and most of the routine clinical parameters were within the normal range, these results might suggest that the depleted immune function accounts for a subclinical malnutrition status in bulimic patients. |
| doi_str_mv | 10.1093/ajcn/57.1.65 |
| format | Article |
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Anthropometry showed no signs of malnutrition in either group. Bulimic patients showed a significant decrease in most of the routine clinical indexes related to red blood cells. Lymphocyte subsets CD2 and CD4 in bulimic patients were lower than in controls, whereas CD8 remained unmodified, leading to a lower CD4:CD8 in bulimic patients. The decreases in CD2 and CD4 numbers might be linked to an impaired cell-mediated immune function, as evaluated by the response to skin tests. The B lymphocyte subset was increased in the bulimic group. Innate immunity was impaired in the bulimic patients. Although anthropometric and most of the routine clinical parameters were within the normal range, these results might suggest that the depleted immune function accounts for a subclinical malnutrition status in bulimic patients.</description><identifier>ISSN: 0002-9165</identifier><identifier>EISSN: 1938-3207</identifier><identifier>DOI: 10.1093/ajcn/57.1.65</identifier><identifier>PMID: 8416667</identifier><identifier>CODEN: AJCNAC</identifier><language>eng</language><publisher>Bethesda, MD: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Adult and adolescent clinical studies ; AIDS/HIV ; Anthropometry ; B-Lymphocytes ; Biological and medical sciences ; Bulimia ; Bulimia - blood ; Bulimia - complications ; Bulimia - immunology ; Bulimia nervosa ; CD4-CD8 Ratio ; Complement System Proteins - analysis ; Eating behavior disorders ; ENFANT ; ERITROCITOS ; ERYTHROCYTE ; Erythrocyte Indices ; ESPAGNE ; ESPANA ; ESTADO NUTRICIONAL ; ETAT NUTRITIONNEL ; FACTEUR IMMUNOLOGIQUE ; FACTORES INMUNOLOGICOS ; Female ; FEMME ; Hemolysis ; Humans ; Hypersensitivity, Delayed ; IMMUNITE CELLULAIRE ; IMMUNITE HUMORALE ; Immunity (Disease) ; Immunity, Cellular ; Immunocompetence ; immunocompetent ; Immunoglobulins - blood ; INMUNIDAD CELULAR ; INMUNIDAD HUMORAL ; JEUNESSE ; JUVENTUD ; LEUCOCITOS ; LEUCOCYTE ; Leukocyte Count ; LINFOCITOS ; LYMPHOCYTE ; Medical research ; Medical sciences ; MUJERES ; NINOS ; Nutrition ; Nutrition Disorders - etiology ; Nutritional Status ; ORGANISME INDICATEUR ; ORGANISMOS INDICADORES ; Psychology. 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Anthropometry showed no signs of malnutrition in either group. Bulimic patients showed a significant decrease in most of the routine clinical indexes related to red blood cells. Lymphocyte subsets CD2 and CD4 in bulimic patients were lower than in controls, whereas CD8 remained unmodified, leading to a lower CD4:CD8 in bulimic patients. The decreases in CD2 and CD4 numbers might be linked to an impaired cell-mediated immune function, as evaluated by the response to skin tests. The B lymphocyte subset was increased in the bulimic group. Innate immunity was impaired in the bulimic patients. Although anthropometric and most of the routine clinical parameters were within the normal range, these results might suggest that the depleted immune function accounts for a subclinical malnutrition status in bulimic patients.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>AIDS/HIV</subject><subject>Anthropometry</subject><subject>B-Lymphocytes</subject><subject>Biological and medical sciences</subject><subject>Bulimia</subject><subject>Bulimia - blood</subject><subject>Bulimia - complications</subject><subject>Bulimia - immunology</subject><subject>Bulimia nervosa</subject><subject>CD4-CD8 Ratio</subject><subject>Complement System Proteins - analysis</subject><subject>Eating behavior disorders</subject><subject>ENFANT</subject><subject>ERITROCITOS</subject><subject>ERYTHROCYTE</subject><subject>Erythrocyte Indices</subject><subject>ESPAGNE</subject><subject>ESPANA</subject><subject>ESTADO NUTRICIONAL</subject><subject>ETAT NUTRITIONNEL</subject><subject>FACTEUR IMMUNOLOGIQUE</subject><subject>FACTORES INMUNOLOGICOS</subject><subject>Female</subject><subject>FEMME</subject><subject>Hemolysis</subject><subject>Humans</subject><subject>Hypersensitivity, Delayed</subject><subject>IMMUNITE CELLULAIRE</subject><subject>IMMUNITE HUMORALE</subject><subject>Immunity (Disease)</subject><subject>Immunity, Cellular</subject><subject>Immunocompetence</subject><subject>immunocompetent</subject><subject>Immunoglobulins - blood</subject><subject>INMUNIDAD CELULAR</subject><subject>INMUNIDAD HUMORAL</subject><subject>JEUNESSE</subject><subject>JUVENTUD</subject><subject>LEUCOCITOS</subject><subject>LEUCOCYTE</subject><subject>Leukocyte Count</subject><subject>LINFOCITOS</subject><subject>LYMPHOCYTE</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>MUJERES</subject><subject>NINOS</subject><subject>Nutrition</subject><subject>Nutrition Disorders - etiology</subject><subject>Nutritional Status</subject><subject>ORGANISME INDICATEUR</subject><subject>ORGANISMOS INDICADORES</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. 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Psychoanalysis. Psychiatry</topic><topic>Psychopathology. 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Anthropometry showed no signs of malnutrition in either group. Bulimic patients showed a significant decrease in most of the routine clinical indexes related to red blood cells. Lymphocyte subsets CD2 and CD4 in bulimic patients were lower than in controls, whereas CD8 remained unmodified, leading to a lower CD4:CD8 in bulimic patients. The decreases in CD2 and CD4 numbers might be linked to an impaired cell-mediated immune function, as evaluated by the response to skin tests. The B lymphocyte subset was increased in the bulimic group. Innate immunity was impaired in the bulimic patients. Although anthropometric and most of the routine clinical parameters were within the normal range, these results might suggest that the depleted immune function accounts for a subclinical malnutrition status in bulimic patients.</abstract><cop>Bethesda, MD</cop><pub>Elsevier Inc</pub><pmid>8416667</pmid><doi>10.1093/ajcn/57.1.65</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adolescent Adult Adult and adolescent clinical studies AIDS/HIV Anthropometry B-Lymphocytes Biological and medical sciences Bulimia Bulimia - blood Bulimia - complications Bulimia - immunology Bulimia nervosa CD4-CD8 Ratio Complement System Proteins - analysis Eating behavior disorders ENFANT ERITROCITOS ERYTHROCYTE Erythrocyte Indices ESPAGNE ESPANA ESTADO NUTRICIONAL ETAT NUTRITIONNEL FACTEUR IMMUNOLOGIQUE FACTORES INMUNOLOGICOS Female FEMME Hemolysis Humans Hypersensitivity, Delayed IMMUNITE CELLULAIRE IMMUNITE HUMORALE Immunity (Disease) Immunity, Cellular Immunocompetence immunocompetent Immunoglobulins - blood INMUNIDAD CELULAR INMUNIDAD HUMORAL JEUNESSE JUVENTUD LEUCOCITOS LEUCOCYTE Leukocyte Count LINFOCITOS LYMPHOCYTE Medical research Medical sciences MUJERES NINOS Nutrition Nutrition Disorders - etiology Nutritional Status ORGANISME INDICATEUR ORGANISMOS INDICADORES Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry REPONSE IMMUNITAIRE RESPUESTA INMUNOLOGICA TRASTORNOS DIGESTIVOS TROUBLE DIGESTIF |
| title | Evaluation of immunocompetence and nutritional status in patients with bulimia nervosa |
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