Association of the ABCB1 3435C>T polymorphism and treatment outcomes in advanced gastric cancer patients treated with paclitaxel-based chemotherapy

We evaluated the frequency of ABCB1 polymorphisms (2677G/T>A and 3435C>T) and studied the association between the polymorphisms and clinical outcomes of paclitaxel-based chemotherapy in advanced gastric cancer patients. This study was performed in 43 gastric cancer patients and a control group...

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Veröffentlicht in:	Oncology reports 2010-01, Vol.23 (1), p.271-278
Hauptverfasser:	HYUN CHANG, SUN YOUNG RHA, JEUNG, Hei-Cheul, CHONG KUN IM, SUNG HOON NOH, JIN JU KIM, HYUN CHEOL CHUNG
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Agents - pharmacology ATP Binding Cassette Transporter, Sub-Family B ATP-Binding Cassette, Sub-Family B, Member 1 - genetics Biological and medical sciences Female Gastroenterology. Liver. Pancreas. Abdomen Genotype Humans Leukocytes, Mononuclear - cytology Male Medical sciences Middle Aged Neoplasm Metastasis Paclitaxel - pharmacology Polymorphism, Genetic Stomach Neoplasms - drug therapy Stomach Neoplasms - genetics Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Treatment Outcome Tumors
Online-Zugang:	Volltext
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