Immunohistochemical Analysis of Macrophages, Myofibroblasts, and Transforming Growth Factor-b Localization during Rat Renal Interstitial Fibrosis Following Long-Term Unilateral Ureteral Obstruction

Renal interstitial fibrosis was induced in rats by chronic unilateral ureteral obstruction (UUO). To identify the mechanisms behind the fibrosis, macrophage influx, myofibroblast involvement, and the localization of transforming growth factor-b (TGF-b, a fibrogenic cytokine) were investigated immuno...

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Veröffentlicht in:Toxicologic pathology 1998-11, Vol.26 (6), p.793-801
Hauptverfasser: Yamate, Jyoji, Okado, Akiko, Kuwamura, Mitsuru, Tsukamoto, Yasuhiro, Ohashi, Fumihito, Kiso, Yasuo, Nakatsuji, Shunji, Kotani, Takao, Sakuma, Sadashige, Lamarre, Jonathan
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Sprache:eng
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