Inhibition of GSK-3β enhances reovirus-induced apoptosis in colon cancer cells

Reovirus functions as an oncolytic agent for many types of cancer including colon cancer. Although most studies have emphasized the role of activated Ras signaling in enhancing reoviral oncolysis in susceptible cells, we note that many colon cancers also display elevated beta -catenin. Thus, it is p...

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Veröffentlicht in:	International journal of oncology 2009-09, Vol.35 (5), p.617-624
Hauptverfasser:	Min, H-J, Koh, S S, Cho, I-R, Srisuttee, R, Park, E-H, Jhun, B H, Kim, Y-G, Oh, S, Kwak, JE, Johnston, R N, Chung, Y-H
Format:	Artikel
Sprache:	eng
Schlagworte:	Reovirus
Online-Zugang:	Volltext
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