Two-year study of cervical cord volume and myelin water in primary progressive multiple sclerosis

Background: Spinal cord involvement in multiple sclerosis (MS) is common and an important element in disability. Previous studies demonstrated smaller cervical cord area at the C2 level in MS compared to controls, and a decrease in cord area over 12 months, most marked in primary progressive MS (PPM...

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Veröffentlicht in:	Multiple sclerosis 2010-06, Vol.16 (6), p.670-677
Hauptverfasser:	Laule, C., Vavasour, IM, Zhao, Y., Traboulsee, AL, Oger, J., Vavasour, JD, Mackay, AL, Li, DKB
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Atrophy - pathology Biological and medical sciences Body Water Brain - pathology Cervical Vertebrae Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Disease Progression Double-Blind Method Female Glatiramer Acetate Humans Immunosuppressive Agents - therapeutic use Magnetic Resonance Imaging Male Medical sciences Middle Aged Multiple sclerosis and variants. Guillain barré syndrome and other inflammatory polyneuropathies. Leukoencephalitis Multiple Sclerosis, Chronic Progressive - drug therapy Multiple Sclerosis, Chronic Progressive - pathology Myelin Sheath - chemistry Myelin Sheath - drug effects Neurology Organ Size - drug effects Peptides - therapeutic use Reproducibility of Results Spinal Cord - drug effects Spinal Cord - pathology Treatment Outcome
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