Characterization of bacterial DNA binding to human neutrophil surface

Bacterial DNA activates neutrophils through a CpG- and TLR9-independent mechanism. Neutrophil activation does not require DNA internalization, suggesting that it results from the interaction of bacterial DNA with a neutrophil surface receptor. The aim of this study was to characterize the interactio...

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Veröffentlicht in:	Laboratory investigation 2008-09, Vol.88 (9), p.926-937
Hauptverfasser:	Fuxman Bass, Juan I, Gabelloni, Maria L, Alvarez, María E, Vermeulen, Mónica E, Russo, Daniela M, Zorreguieta, Ángeles, Geffner, Jorge R, Trevani, Analía S
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Base Sequence Biofilms Biological and medical sciences Biotechnology Cells, Cultured DNA Primers DNA, Bacterial - metabolism Escherichia coli - genetics Fundamental and applied biological sciences. Psychology Humans Investigative techniques, diagnostic techniques (general aspects) Laboratory Medicine Medical sciences Medicine Medicine & Public Health Neutrophils - metabolism Pathology research-article
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