Transmembrane Ca2+ gradient and function of membrane proteins
This review will focus on the recent advance in the study of effect of transmembrane Ca2+ gradient on the function of membrane proteins. It consits of two parts: 1. Transmembrane Ca2+ gradient and sarcoplasmic reticulum Ca(2+)-ATPase; 2. Effect of transmembrane Ca2+ gradient on the components and co...
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Veröffentlicht in: | Bioscience reports 1995-10, Vol.15 (5), p.351-364 |
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creator | Yang, F Y Huang, Y G Tu, Y P |
description | This review will focus on the recent advance in the study of effect of transmembrane Ca2+ gradient on the function of membrane proteins. It consits of two parts: 1. Transmembrane Ca2+ gradient and sarcoplasmic reticulum Ca(2+)-ATPase; 2. Effect of transmembrane Ca2+ gradient on the components and coupling of cAMP signal transduction pathway. The results obtained indicate that a proper transmembrane Ca2+ gradient may play an important role in modulating the conformation and activity of SR Ca(2+)-ATPase and the function of membrane proteins involved in the cAMP signal transduction by mediating the physical state change of the membrane phospholipids. |
doi_str_mv | 10.1007/BF01788367 |
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The results obtained indicate that a proper transmembrane Ca2+ gradient may play an important role in modulating the conformation and activity of SR Ca(2+)-ATPase and the function of membrane proteins involved in the cAMP signal transduction by mediating the physical state change of the membrane phospholipids.</description><subject>Animals</subject><subject>Calcium - metabolism</subject><subject>Calcium-Transporting ATPases - metabolism</subject><subject>Humans</subject><subject>Ion Transport</subject><subject>Membrane Proteins - metabolism</subject><subject>Sarcoplasmic Reticulum - metabolism</subject><subject>Signal Transduction</subject><issn>0144-8463</issn><issn>1573-4935</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1995</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkDtPwzAUhS0EKqWwsCNlYgAF_LjxY2CAiAJSJZYyR45zjYKapNjJwL_HqFWZznA_nXv0EXLJ6B2jVN0_LSlTWgupjsicFUrkYERxTOaUAeQapDglZzF-UUrTAWZkpjUvqFBz8rAOto8ddnVKzErLb7PPYJsW-zGzfZP5qXdjO_TZ4LMDtg3DiG0fz8mJt5uIF_tckI_l87p8zVfvL2_l4yp3nMGYK2Ek10wa0RguwYGrFXBE5jEB6L0DAVprL7lNa31jlLUGJHCwtawLsSDXu970-HvCOFZdGx1uNmnMMMVKFWCAGZHAmx3owhBjQF9tQ9vZ8FMxWv25qv5dJfhq3zrVHTYHdC9H_AIO2GJW</recordid><startdate>199510</startdate><enddate>199510</enddate><creator>Yang, F Y</creator><creator>Huang, Y G</creator><creator>Tu, Y P</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199510</creationdate><title>Transmembrane Ca2+ gradient and function of membrane proteins</title><author>Yang, F Y ; Huang, Y G ; Tu, Y P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c214t-7396281693d9264c4cb742ee1fec21effc434888f62a846fd97aa946424ab6b53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1995</creationdate><topic>Animals</topic><topic>Calcium - metabolism</topic><topic>Calcium-Transporting ATPases - metabolism</topic><topic>Humans</topic><topic>Ion Transport</topic><topic>Membrane Proteins - metabolism</topic><topic>Sarcoplasmic Reticulum - metabolism</topic><topic>Signal Transduction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yang, F Y</creatorcontrib><creatorcontrib>Huang, Y G</creatorcontrib><creatorcontrib>Tu, Y P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Bioscience reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yang, F Y</au><au>Huang, Y G</au><au>Tu, Y P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Transmembrane Ca2+ gradient and function of membrane proteins</atitle><jtitle>Bioscience reports</jtitle><addtitle>Biosci Rep</addtitle><date>1995-10</date><risdate>1995</risdate><volume>15</volume><issue>5</issue><spage>351</spage><epage>364</epage><pages>351-364</pages><issn>0144-8463</issn><eissn>1573-4935</eissn><abstract>This review will focus on the recent advance in the study of effect of transmembrane Ca2+ gradient on the function of membrane proteins. 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subjects | Animals Calcium - metabolism Calcium-Transporting ATPases - metabolism Humans Ion Transport Membrane Proteins - metabolism Sarcoplasmic Reticulum - metabolism Signal Transduction |
title | Transmembrane Ca2+ gradient and function of membrane proteins |
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