Genetic association studies of schizophrenia using the 8p21-22 genes: prepronociceptin (PNOC), neuronal nicotinic cholinergic receptor alpha polypeptide 2 (CHRNA2) and arylamine N-acetyltransferase 1 (NAT1)

Schizophrenia is a common, genetically heterogeneous disorder with a lifetime prevalence of approximately 1% in the general population. Linkage studies of affected families have now strongly implicated a susceptibility locus on chromosome 8p21-22. Tests of allelic association with markers on 8p21-22...

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Veröffentlicht in:	European journal of human genetics : EJHG 2001-06, Vol.9 (6), p.469-472
Hauptverfasser:	Blaveri, E, Kalsi, G, Lawrence, J, Quested, D, Moorey, H, Lamb, G, Kohen, D, Shiwach, R, Chowdhury, U, Curtis, D, McQuillin, A, Gramoustianou, E S, Gurling, H M
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions Acetyltransferase Alleles Arylamine N-acetyltransferase Arylamine N-Acetyltransferase - genetics Brain research Case-Control Studies Chromosome 8 Chromosomes Chromosomes, Human, Pair 8 Deoxyribonucleic acid DNA Enzymes Gene frequency Genealogy Genes Genetics Genotype Handbooks Humans Hypotheses Laboratories Mental disorders Mutation N-Acetyltransferase N-acetyltransferase 1 Nucleotides Polymerase Chain Reaction Polymorphism, Restriction Fragment Length Polypeptides Population studies Protein Precursors - genetics Psychiatry Quantitative Trait, Heritable Receptors, Nicotinic - genetics Receptors, Opioid - genetics Repetitive Sequences, Nucleic Acid Schizophrenia Schizophrenia - genetics Studies Susceptibility University colleges
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