CALCIUM DEPENDENT REGULATION OF BRAIN AND CARDIAC MUSCLE ADENYLATE CYCLASE

The very close interdependence of Ca2+ and hormones in the overall metabolism of cyclic nucleotides has recently been emphasized by Cheung. Clearly the results presented here show that [Ca2+] in the physiological range (less than 10(-7) M to greater than 10(-6) M) has profound effects on the activit...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 1980-12, Vol.356 (1), p.220-231
Hauptverfasser:	Potter, James D., Piascik, Michael T., Wisler, Patricia L., Robertson, Stephen P., Johnson, Carl L.
Format:	Artikel
Sprache:	eng
Schlagworte:	3',5'-Cyclic-AMP Phosphodiesterases - metabolism 3',5'-Cyclic-GMP Phosphodiesterases - metabolism Adenylyl Cyclases - metabolism Animals Brain - enzymology Calcium - pharmacology Calmodulin - metabolism Cations, Divalent Cyclic Nucleotide Phosphodiesterases, Type 1 Enzyme Activation Guinea Pigs Kinetics Myocardium - enzymology Trifluoperazine - pharmacology Troponin - pharmacology Troponin I Tyrosine - analysis
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