A Brownian-ratchet DNA pump with applications to single-nucleotide polymorphism genotyping

We have fabricated a micron-scale device capable of transporting DNA oligomers using Brownian ratchets. The ratchet potential is generated by applying a voltage difference to interdigitated electrodes. Cycling between the charged state and a discharged, free-diffusion state rectifies the Brownian mo...

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Bibliographische Detailangaben

Veröffentlicht in:	Applied physics. A, Materials science & processing Materials science & processing, 2002-08, Vol.75 (2), p.275-278
Hauptverfasser:	Bader, J.S., Deem, M.W., Hammond, R.W., Henck, S.A., Simpson, J.W., Rothberg, J.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Brownian movement Charged particles Diffusion Electric potential Electrodes Genes Oligomers Transport properties
Online-Zugang:	Volltext
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