Glioblastoma multiforme in children: experience at Hospital Infantil de Mexico Federico Gomez
Objective To evaluate clinical evolution of pediatric patients diagnosed with glioblastoma multiforme (GBM) at Hospital Infantil de México Federico Gómez. Methods Cases of patients treated from January to May, 2007, were included in this study. Variables analyzed were: age, diagnosis, size of tumor,...
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| Veröffentlicht in: | Child's nervous system 2009-05, Vol.25 (5), p.551-557 |
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| creator | Sánchez-Herrera, Federico Castro-Sierra, Eduardo Gordillo-Domínguez, Luis Felipe Vaca-Ruiz, Miguel Angel Santana-Montero, Blanca Perezpeña-Diazconti, Mario González-Carranza, Vicente Torres-García, Samuel Chico-Ponce de León, Fernando |
| description | Objective To evaluate clinical evolution of pediatric patients diagnosed with glioblastoma multiforme (GBM) at Hospital Infantil de México Federico Gómez. Methods Cases of patients treated from January to May, 2007, were included in this study. Variables analyzed were: age, diagnosis, size of tumor, histopathological description, degree of resection, time of stay in hospital, complications and outcome using Pearson's chi-squared test and logistic regression. Conclusion Sixteen patients were identified. Mean age of presentation was 8.8. An increased frequency of complications was observed in younger patients and longer survival rates in patients with greater resections; main mode of presentation was directly related to intracranial hypertension; size of tumor was not related to evolution or outcome. Modern histological classifications especially designed for children are deemed necessary to accurately diagnose GBM. |
| doi_str_mv | 10.1007/s00381-008-0780-8 |
| format | Article |
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Methods Cases of patients treated from January to May, 2007, were included in this study. Variables analyzed were: age, diagnosis, size of tumor, histopathological description, degree of resection, time of stay in hospital, complications and outcome using Pearson's chi-squared test and logistic regression. Conclusion Sixteen patients were identified. Mean age of presentation was 8.8. An increased frequency of complications was observed in younger patients and longer survival rates in patients with greater resections; main mode of presentation was directly related to intracranial hypertension; size of tumor was not related to evolution or outcome. Modern histological classifications especially designed for children are deemed necessary to accurately diagnose GBM.</description><identifier>ISSN: 0256-7040</identifier><identifier>EISSN: 1433-0350</identifier><identifier>DOI: 10.1007/s00381-008-0780-8</identifier><identifier>PMID: 19148652</identifier><language>eng</language><publisher>Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag</publisher><subject>Age Factors ; Brain Neoplasms - complications ; Brain Neoplasms - diagnosis ; Brain Neoplasms - pathology ; Brain Neoplasms - physiopathology ; Chi-Square Distribution ; Child ; Childhood brain tumors ; Female ; Glioblastoma - complications ; Glioblastoma - diagnosis ; Glioblastoma - pathology ; Glioblastoma - physiopathology ; Glioblastoma multiforme ; Hospitals, Pediatric ; Humans ; Intracranial Hypertension - etiology ; Intracranial Hypertension - physiopathology ; Logistic Models ; Male ; Medicine ; Medicine & Public Health ; Mexico ; Multivariate Analysis ; Neurosciences ; Neurosurgery ; Original Paper ; Prognosis ; Risk Factors ; Survival Rate</subject><ispartof>Child's nervous system, 2009-05, Vol.25 (5), p.551-557</ispartof><rights>Springer-Verlag 2009</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c398t-738448cfda88e9e516323ad4555becc8562e52cd841fe25c0f37f0a3757cc59c3</citedby><cites>FETCH-LOGICAL-c398t-738448cfda88e9e516323ad4555becc8562e52cd841fe25c0f37f0a3757cc59c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00381-008-0780-8$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00381-008-0780-8$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19148652$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sánchez-Herrera, Federico</creatorcontrib><creatorcontrib>Castro-Sierra, Eduardo</creatorcontrib><creatorcontrib>Gordillo-Domínguez, Luis Felipe</creatorcontrib><creatorcontrib>Vaca-Ruiz, Miguel Angel</creatorcontrib><creatorcontrib>Santana-Montero, Blanca</creatorcontrib><creatorcontrib>Perezpeña-Diazconti, Mario</creatorcontrib><creatorcontrib>González-Carranza, Vicente</creatorcontrib><creatorcontrib>Torres-García, Samuel</creatorcontrib><creatorcontrib>Chico-Ponce de León, Fernando</creatorcontrib><title>Glioblastoma multiforme in children: experience at Hospital Infantil de Mexico Federico Gomez</title><title>Child's nervous system</title><addtitle>Childs Nerv Syst</addtitle><addtitle>Childs Nerv Syst</addtitle><description>Objective To evaluate clinical evolution of pediatric patients diagnosed with glioblastoma multiforme (GBM) at Hospital Infantil de México Federico Gómez. Methods Cases of patients treated from January to May, 2007, were included in this study. Variables analyzed were: age, diagnosis, size of tumor, histopathological description, degree of resection, time of stay in hospital, complications and outcome using Pearson's chi-squared test and logistic regression. Conclusion Sixteen patients were identified. Mean age of presentation was 8.8. An increased frequency of complications was observed in younger patients and longer survival rates in patients with greater resections; main mode of presentation was directly related to intracranial hypertension; size of tumor was not related to evolution or outcome. Modern histological classifications especially designed for children are deemed necessary to accurately diagnose GBM.</description><subject>Age Factors</subject><subject>Brain Neoplasms - complications</subject><subject>Brain Neoplasms - diagnosis</subject><subject>Brain Neoplasms - pathology</subject><subject>Brain Neoplasms - physiopathology</subject><subject>Chi-Square Distribution</subject><subject>Child</subject><subject>Childhood brain tumors</subject><subject>Female</subject><subject>Glioblastoma - complications</subject><subject>Glioblastoma - diagnosis</subject><subject>Glioblastoma - pathology</subject><subject>Glioblastoma - physiopathology</subject><subject>Glioblastoma multiforme</subject><subject>Hospitals, Pediatric</subject><subject>Humans</subject><subject>Intracranial Hypertension - etiology</subject><subject>Intracranial Hypertension - physiopathology</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Mexico</subject><subject>Multivariate Analysis</subject><subject>Neurosciences</subject><subject>Neurosurgery</subject><subject>Original Paper</subject><subject>Prognosis</subject><subject>Risk Factors</subject><subject>Survival Rate</subject><issn>0256-7040</issn><issn>1433-0350</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1v1DAURS0EotOWH8AGvKKrwPNXbLNDFZ1WKmLRdllZHue5uEriwU6kwq8nVUZi19W70jv3Lg4h7xl8ZgD6SwUQhjUApgFtoDGvyIZJIRoQCl6TDXDVNhokHJHjWh8BmDLcviVHzDJpWsU35H7bp7zrfZ3y4Okw91OKuQxI00jDr9R3BcevFJ_2WBKOAamf6GWu-zT5nl6N0Y9T6mmH9Ac-pZDpBXYLuYRtHvDvKXkTfV_x3eGekLuL77fnl831z-3V-bfrJghrpkYLI6UJsfPGoEXFWsGF76RSaochGNVyVDx0RrKIXAWIQkfwQisdgrJBnJCzdXdf8u8Z6-SGVAP2vR8xz9VpJY0FbfVCfnqRbDUDaxUsIFvBUHKtBaPblzT48scxcM_23WrfLfbds31nls6Hw_i8G7D73zjoXgC-AnV5jQ9Y3GOey7ioeXH141qKPjv_UFJ1dzccmADWMim5Fv8AYY6Y3w</recordid><startdate>20090501</startdate><enddate>20090501</enddate><creator>Sánchez-Herrera, Federico</creator><creator>Castro-Sierra, Eduardo</creator><creator>Gordillo-Domínguez, Luis Felipe</creator><creator>Vaca-Ruiz, Miguel Angel</creator><creator>Santana-Montero, Blanca</creator><creator>Perezpeña-Diazconti, Mario</creator><creator>González-Carranza, Vicente</creator><creator>Torres-García, Samuel</creator><creator>Chico-Ponce de León, Fernando</creator><general>Berlin/Heidelberg : Springer-Verlag</general><general>Springer-Verlag</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7TK</scope></search><sort><creationdate>20090501</creationdate><title>Glioblastoma multiforme in children: experience at Hospital Infantil de Mexico Federico Gomez</title><author>Sánchez-Herrera, Federico ; Castro-Sierra, Eduardo ; Gordillo-Domínguez, Luis Felipe ; Vaca-Ruiz, Miguel Angel ; Santana-Montero, Blanca ; Perezpeña-Diazconti, Mario ; González-Carranza, Vicente ; Torres-García, Samuel ; Chico-Ponce de León, Fernando</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c398t-738448cfda88e9e516323ad4555becc8562e52cd841fe25c0f37f0a3757cc59c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Age Factors</topic><topic>Brain Neoplasms - complications</topic><topic>Brain Neoplasms - diagnosis</topic><topic>Brain Neoplasms - pathology</topic><topic>Brain Neoplasms - physiopathology</topic><topic>Chi-Square Distribution</topic><topic>Child</topic><topic>Childhood brain tumors</topic><topic>Female</topic><topic>Glioblastoma - complications</topic><topic>Glioblastoma - diagnosis</topic><topic>Glioblastoma - pathology</topic><topic>Glioblastoma - physiopathology</topic><topic>Glioblastoma multiforme</topic><topic>Hospitals, Pediatric</topic><topic>Humans</topic><topic>Intracranial Hypertension - etiology</topic><topic>Intracranial Hypertension - physiopathology</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Mexico</topic><topic>Multivariate Analysis</topic><topic>Neurosciences</topic><topic>Neurosurgery</topic><topic>Original Paper</topic><topic>Prognosis</topic><topic>Risk Factors</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sánchez-Herrera, Federico</creatorcontrib><creatorcontrib>Castro-Sierra, Eduardo</creatorcontrib><creatorcontrib>Gordillo-Domínguez, Luis Felipe</creatorcontrib><creatorcontrib>Vaca-Ruiz, Miguel Angel</creatorcontrib><creatorcontrib>Santana-Montero, Blanca</creatorcontrib><creatorcontrib>Perezpeña-Diazconti, Mario</creatorcontrib><creatorcontrib>González-Carranza, Vicente</creatorcontrib><creatorcontrib>Torres-García, Samuel</creatorcontrib><creatorcontrib>Chico-Ponce de León, Fernando</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Neurosciences Abstracts</collection><jtitle>Child's nervous system</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sánchez-Herrera, Federico</au><au>Castro-Sierra, Eduardo</au><au>Gordillo-Domínguez, Luis Felipe</au><au>Vaca-Ruiz, Miguel Angel</au><au>Santana-Montero, Blanca</au><au>Perezpeña-Diazconti, Mario</au><au>González-Carranza, Vicente</au><au>Torres-García, Samuel</au><au>Chico-Ponce de León, Fernando</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Glioblastoma multiforme in children: experience at Hospital Infantil de Mexico Federico Gomez</atitle><jtitle>Child's nervous system</jtitle><stitle>Childs Nerv Syst</stitle><addtitle>Childs Nerv Syst</addtitle><date>2009-05-01</date><risdate>2009</risdate><volume>25</volume><issue>5</issue><spage>551</spage><epage>557</epage><pages>551-557</pages><issn>0256-7040</issn><eissn>1433-0350</eissn><abstract>Objective To evaluate clinical evolution of pediatric patients diagnosed with glioblastoma multiforme (GBM) at Hospital Infantil de México Federico Gómez. 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| subjects | Age Factors Brain Neoplasms - complications Brain Neoplasms - diagnosis Brain Neoplasms - pathology Brain Neoplasms - physiopathology Chi-Square Distribution Child Childhood brain tumors Female Glioblastoma - complications Glioblastoma - diagnosis Glioblastoma - pathology Glioblastoma - physiopathology Glioblastoma multiforme Hospitals, Pediatric Humans Intracranial Hypertension - etiology Intracranial Hypertension - physiopathology Logistic Models Male Medicine Medicine & Public Health Mexico Multivariate Analysis Neurosciences Neurosurgery Original Paper Prognosis Risk Factors Survival Rate |
| title | Glioblastoma multiforme in children: experience at Hospital Infantil de Mexico Federico Gomez |
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