Immediate-Early Expression of a Recombinant Antigen by Modified Vaccinia Virus Ankara Breaks the Immunodominance of Strong Vector-Specific B8R Antigen in Acute and Memory CD8 T-Cell Responses

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Veröffentlicht in:	Journal of Virology 2010-09, Vol.84 (17), p.8743-8752
Hauptverfasser:	Baur, Karen, Brinkmann, Kay, Schweneker, Marc, Pätzold, Juliane, Meisinger-Henschel, Christine, Hermann, Judith, Steigerwald, Robin, Chaplin, Paul, Suter, Mark, Hausmann, Jürgen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Viral - blood Antigens, Viral - genetics Antigens, Viral - immunology Base Sequence CD8 Antigens - genetics CD8 Antigens - immunology CD8-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - virology Cell Line Cells, Cultured Chick Embryo Cricetinae Female Gene Expression Genes, Immediate-Early Genetic Vectors - genetics Genetic Vectors - immunology Humans Mice Mice, Inbred C57BL Molecular Sequence Data Ovalbumin - genetics Ovalbumin - immunology Promoter Regions, Genetic Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - immunology Vaccines and Antiviral Agents Vaccinia - immunology Vaccinia - virology Vaccinia virus Vaccinia virus - chemistry Vaccinia virus - genetics Vaccinia virus - immunology Viral Vaccines - genetics Viral Vaccines - immunology
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