Marrow graft rejection by repeated transfusions of allogeneic donor spleen cells

Many hematological diseases require long-term transfusion support, which causes production of donor-reactive antibodies in sensitized recipients. Sensitized patients are at an increased risk for graft rejection when they undergo allogeneic hematopoietic stem cell transplantation (allo-HSCT). Here, w...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2007-10, Vol.40 (7), p.691-698
Hauptverfasser:	XU, L. H, FANG, J. P, HUANG, W. G, XU, H. G, WENG, W. J, KAO, G. S, LE, Y
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animal models Animals Antibodies Biological and medical sciences Bone marrow Bone marrow transplantation Bone Marrow Transplantation - immunology Bone Marrow Transplantation - mortality Bone marrow, stem cells transplantation. Graft versus host reaction Cell Transplantation - adverse effects Complement system Cytotoxicity Engraftment Graft rejection Graft Rejection - etiology Grafting Hematological diseases Hematopoietic stem cells Homing Humans Isoantibodies - blood Male Medical sciences Mice Mice, Inbred BALB C Mice, Inbred C57BL Models, Animal Rejection Spleen Spleen - cytology Stem cell transplantation Stem cells Tissue Donors Toxicity Transfusion Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Transplantation, Homologous
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