Non-invasive studies of peripheral vascular compliance using a non-occluding photoplethysmographic method
A non-invasive technique is implemented to measure a peripheral vascular compliance index Cindex, using an infrared photoplethysmographic waveform as an indicator of intravascular volume change and a continuous blood pressure monitor to measure the blood pressure during each heart-beat. The non-line...
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| Veröffentlicht in: | Medical & biological engineering & computing 1998-11, Vol.36 (6), p.748-753 |
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| creator | LOPEZ-BELTRAN, E. A BLACKSHEAR, P. L FINKELSTEIN, S. M COHN, J. N |
| description | A non-invasive technique is implemented to measure a peripheral vascular compliance index Cindex, using an infrared photoplethysmographic waveform as an indicator of intravascular volume change and a continuous blood pressure monitor to measure the blood pressure during each heart-beat. The non-linear behaviour of Cindex with pressure and the effect of age on Cindex are studied in 62 males (15-73 years). Repeatability tests and the effect of ice-water exposure of a portion of a limb are studied in 10 and 14 subjects, respectively. For each individual, Cindex measurements are taken at discrete values of local mean arterial pressure (Pmean), and a Cindex against Pmean plot is obtained. There is a statistically significant difference (p < 0.05) in Cindex for the lower values of Pmean (60-100 mmHg) between two age groups formed (15-52 and 58-73 years). The cold-pressor test (CPT) shows a 68% median decrease in Cindex, with an inter-quartile range of 60-77%, in a matter of seconds. The results suggest that Cindex may be a useful noninvasive indicator of peripheral vascular compliance in humans. |
| doi_str_mv | 10.1007/bf02518879 |
| format | Article |
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A</creatorcontrib><creatorcontrib>BLACKSHEAR, P. L</creatorcontrib><creatorcontrib>FINKELSTEIN, S. M</creatorcontrib><creatorcontrib>COHN, J. N</creatorcontrib><title>Non-invasive studies of peripheral vascular compliance using a non-occluding photoplethysmographic method</title><title>Medical & biological engineering & computing</title><addtitle>Med Biol Eng Comput</addtitle><description>A non-invasive technique is implemented to measure a peripheral vascular compliance index Cindex, using an infrared photoplethysmographic waveform as an indicator of intravascular volume change and a continuous blood pressure monitor to measure the blood pressure during each heart-beat. The non-linear behaviour of Cindex with pressure and the effect of age on Cindex are studied in 62 males (15-73 years). Repeatability tests and the effect of ice-water exposure of a portion of a limb are studied in 10 and 14 subjects, respectively. For each individual, Cindex measurements are taken at discrete values of local mean arterial pressure (Pmean), and a Cindex against Pmean plot is obtained. There is a statistically significant difference (p < 0.05) in Cindex for the lower values of Pmean (60-100 mmHg) between two age groups formed (15-52 and 58-73 years). The cold-pressor test (CPT) shows a 68% median decrease in Cindex, with an inter-quartile range of 60-77%, in a matter of seconds. The results suggest that Cindex may be a useful noninvasive indicator of peripheral vascular compliance in humans.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age</subject><subject>Aged</subject><subject>Aging - physiology</subject><subject>Biological and medical sciences</subject><subject>Biomedical equipment</subject><subject>Blood Pressure</subject><subject>Compliance</subject><subject>Fingers - blood supply</subject><subject>Hemodynamics</subject><subject>Humans</subject><subject>Indicators</subject><subject>Infrared</subject><subject>Infrared devices</subject><subject>Investigative techniques, diagnostic techniques (general aspects)</subject><subject>Male</subject><subject>Males</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Miscellaneous. Technology</subject><subject>Monitors</subject><subject>Pathology. Cytology. Biochemistry. Spectrometry. 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A</au><au>BLACKSHEAR, P. L</au><au>FINKELSTEIN, S. M</au><au>COHN, J. N</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Non-invasive studies of peripheral vascular compliance using a non-occluding photoplethysmographic method</atitle><jtitle>Medical & biological engineering & computing</jtitle><addtitle>Med Biol Eng Comput</addtitle><date>1998-11-01</date><risdate>1998</risdate><volume>36</volume><issue>6</issue><spage>748</spage><epage>753</epage><pages>748-753</pages><issn>0140-0118</issn><eissn>1741-0444</eissn><abstract>A non-invasive technique is implemented to measure a peripheral vascular compliance index Cindex, using an infrared photoplethysmographic waveform as an indicator of intravascular volume change and a continuous blood pressure monitor to measure the blood pressure during each heart-beat. The non-linear behaviour of Cindex with pressure and the effect of age on Cindex are studied in 62 males (15-73 years). Repeatability tests and the effect of ice-water exposure of a portion of a limb are studied in 10 and 14 subjects, respectively. For each individual, Cindex measurements are taken at discrete values of local mean arterial pressure (Pmean), and a Cindex against Pmean plot is obtained. There is a statistically significant difference (p < 0.05) in Cindex for the lower values of Pmean (60-100 mmHg) between two age groups formed (15-52 and 58-73 years). The cold-pressor test (CPT) shows a 68% median decrease in Cindex, with an inter-quartile range of 60-77%, in a matter of seconds. The results suggest that Cindex may be a useful noninvasive indicator of peripheral vascular compliance in humans.</abstract><cop>Heidelberg</cop><pub>Springer</pub><pmid>10367467</pmid><doi>10.1007/bf02518879</doi><tpages>6</tpages></addata></record> |
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| subjects | Adolescent Adult Age Aged Aging - physiology Biological and medical sciences Biomedical equipment Blood Pressure Compliance Fingers - blood supply Hemodynamics Humans Indicators Infrared Infrared devices Investigative techniques, diagnostic techniques (general aspects) Male Males Medical sciences Middle Aged Miscellaneous. Technology Monitors Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Patient monitoring Photoplethysmography - methods Reproducibility Volume measurement Waveforms |
| title | Non-invasive studies of peripheral vascular compliance using a non-occluding photoplethysmographic method |
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