Transcription of the Transforming Growth Factor b Activating Integrin b8 Subunit Is Regulated by SP3, AP-1, and the p38 Pathway

Integrin avb8 is a critical regulator of transforming growth factor b activation in vasculogenesis during development, immune regulation, and endothelial/epithelial-mesenchymal homeostasis. Recent studies have suggested roles for integrin b8 in the pathogenesis of chronic obstructive pulmonary disea...

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Veröffentlicht in:	The Journal of biological chemistry 2010-08, Vol.285 (32), p.24695-24706
Hauptverfasser:	Markovics, Jennifer A, Araya, Jun, Cambier, Stephanie, Jablons, David, Hill, Arthur, Wolters, Paul J, Nishimura, Stephen L
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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