Stimulation of Platelet-derived Growth Factor Receptor b (PDGFRb) Activates ADAM17 and Promotes Metalloproteinase-dependent Cross-talk between the PDGFRb and Epidermal Growth Factor Receptor (EGFR) Signaling Pathways

Binding of the platelet-derived growth factor (PDGF)-B to its receptor PDGFRb promotes proliferation, migration, and recruitment of pericytes and smooth muscle cells to endothelial cells, serving to stabilize developing blood vessels. The main goals of this study were to determine whether the extrac...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of biological chemistry 2010-08, Vol.285 (32), p.25024-25032
Hauptverfasser:	Mendelson, Karen, Swendeman, Steven, Saftig, Paul, Blobel, Carl P
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!