Particle Size and Bulk Powder Flow Control by Supercritical Antisolvent Precipitation

The purpose of this study was to use silicas for controlling the particle size of a poorly soluble drug in the micrometer to submicrometer range and enhancing the flowability of those particles in a supercritical fluid process. The concept used consists in entrapping a fast precipitated drug into th...

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Veröffentlicht in:	Industrial & engineering chemistry research 2009-06, Vol.48 (11), p.5302-5309
Hauptverfasser:	Thakur, Ranjit, Hudgins, Auburn E, Goncalves, Elisabete, Muhrer, Gerhard
Format:	Artikel
Sprache:	eng
Schlagworte:	Applied sciences Chemical engineering Exact sciences and technology Materials and Interfaces
Online-Zugang:	Volltext
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