Detection of cytokeratin 19 mRNA and CYFRA 21-1 (cytokeratin 19 fragments) in blood of Tunisian women with breast cancer

Cytokeratin 19 (CK19) is an acidic protein of 40 kDa that is part of the cytoskeleton of epithelial cells. It is highly expressed by all epithelial cells and represents a useful indicator of epithelial differentiation. The soluble fragment of CK19 (CYFRA 21-1) can be a useful circulating tumor marke...

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Veröffentlicht in:	The International journal of biological markers 2008-10, Vol.23 (4), p.238-243
Hauptverfasser:	MARRAKCHI, R, OUERHANIL, S, BENAMMAR, S, ROUISSI, K, BOUHAHA, R, BOUGATEF, K, MESSAI, Y, KHADIMALLAH, I, RAHAL, K, BEN AMMAR-ELGAAIED, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analytical, structural and metabolic biochemistry Antigens, Neoplasm - blood Antigens, Neoplasm - genetics Biological and medical sciences Biomarkers, Tumor - blood Biomarkers, Tumor - genetics Breast Neoplasms - blood Breast Neoplasms - genetics Breast Neoplasms - pathology Breast Neoplasms - secondary Case-Control Studies Cell Line, Tumor Female Fundamental and applied biological sciences. Psychology Gene Expression Gene Expression Regulation, Neoplastic Humans Investigative techniques, diagnostic techniques (general aspects) Keratin-19 - blood Keratin-19 - genetics Keratins - blood Keratins - genetics Medical sciences Middle Aged Molecular biophysics Neoplasm Staging Prognosis RNA, Messenger - blood RNA, Messenger - genetics Sensitivity and Specificity Tunisia
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