Nitric oxide and cyclic GMP regulate early events in agrin signaling in skeletal muscle cells

Agrin released from motor nerve terminals directs differentiation of the vertebrate neuromuscular junction (NMJ). Activity of nitric oxide synthase (NOS), guanylate cyclase (GC), and cyclic GMP-dependent protein kinase (PKG) contributes to agrin signaling in embryonic frog and chick muscle cells. St...

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Veröffentlicht in:	Experimental cell research 2010-07, Vol.316 (12), p.1935-1945
Hauptverfasser:	Godfrey, Earl W., Schwarte, Russell C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Agrin Agrin - metabolism Animals Anura Cells, Cultured Cellular biology Cyclic GMP Cyclic GMP - metabolism Cytoskeleton Mice Muscle cells Muscle, Skeletal - metabolism Musculoskeletal system Neuromuscular junction Nitric oxide Nitric Oxide - metabolism Nitric Oxide Synthase - genetics Nitric Oxide Synthase - metabolism Protein Isoforms - metabolism Rac1 Receptors, Cholinergic - metabolism Signal Transduction
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