Smad7 Regulates the Adult Neural Stem/Progenitor Cell Pool in a Transforming Growth Factor ?- and Bone Morphogenetic Protein-Independent Manner

Members of the transforming growth factor ? (TGF-?) family of proteins modulate the proliferation, differentiation, and survival of many different cell types. Neural stem and progenitor cells (NPCs) in the adult brain are inhibited in their proliferation by TGF-? and by bone morphogenetic proteins (...

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Veröffentlicht in:Molecular and cellular biology 2010-07, Vol.30 (14), p.3685-3694
Hauptverfasser: Krampert, Monika, Chirasani, Sridhar Reddy, Wachs, Frank-Peter, Aigner, Robert, Bogdahn, Ulrich, Yingling, Jonathan M, Heldin, Carl-Henrik, Aigner, Ludwig, Heuchel, Rainer
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Sprache:eng
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