Homeostatic Role of Transforming Growth Factor-b in the Oral Cavity and Esophagus of Mice and Its Expression by Mast Cells in These Tissues

Transforming growth factor-b (TGF-b) is a pleiotropic growth factor; its overexpression has been implicated in many diseases, making it a desirable target for therapeutic neutralization. In initial safety studies, mice were chronically treated (three times per week) with high doses (50 mg/kg) of a m...

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Veröffentlicht in:	The American journal of pathology 2009-06, Vol.174 (6), p.2137-2149
Hauptverfasser:	Vitsky, A, Waire, J, Pawliuk, R, Bond, A, Matthews, D, LaCasse, E, Hawes, M L, Nelson, C, Richards, S, Piepenhagen, P A, Garman, R D, Andrews, L, Thurberg, B L, Lonning, S
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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