The gastric antisecretory and antiulcer activity of MK-447, an enhancer of prostaglandin synthesis

MK-447 is a free radical scavenger and in the arachidonic acid cascade it reduces the accumulation of the endoperoxide, PGG 2. It also enhances the formation of the endoperoxide, PGH 2, and other prostaglandins. Since many prostaglandins reduce gastric acid secretion and protect the gastric mucosa f...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Life sciences (1973) 1980-12, Vol.27 (25), p.2483-2487
Hauptverfasser:	Shriver, D.A., Thompson, J.W., Scott, C.K., Moore, L.E., Woolf, G., Mack, V.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Ulcer Agents Aspirin - pharmacology Butylated Hydroxytoluene - analogs & derivatives Butylated Hydroxytoluene - pharmacology Dogs Ethanol - pharmacology Female Gastric Juice - drug effects Gastric Juice - metabolism Gastric Mucosa - drug effects Gastric Mucosa - physiopathology Male Rats
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!