Cholinesterase in muscle of dystrophic hamsters (Bio-40.54)
Isozyme patterns of cholinesterase (ChE) from heart, tongue, and skeletal muscle of normal and dystrophic hamsters are presented. Two principal bands, bands 1 and 2, were evaluated. Band 1 migrates faster towards the anode than does band 2. While bands 1 and 2 stain for AChE and were found in contro...
Gespeichert in:
| Veröffentlicht in: | Neurochemical research 1980-12, Vol.5 (12), p.1221-1230 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1230 |
|---|---|
| container_issue | 12 |
| container_start_page | 1221 |
| container_title | Neurochemical research |
| container_volume | 5 |
| creator | Henderson, N S Tweedle, C D Kabara, J J |
| description | Isozyme patterns of cholinesterase (ChE) from heart, tongue, and skeletal muscle of normal and dystrophic hamsters are presented. Two principal bands, bands 1 and 2, were evaluated. Band 1 migrates faster towards the anode than does band 2. While bands 1 and 2 stain for AChE and were found in control muscles, only band 2 was stained by a pseudocholinesterase (BuChE) and was decreased in samples from dystrophic hamsters. The decrease in BuChE was most pronounced in dystrophic heart muscle. The low level of BuChE measured for dystrophic animal tissue was similar to isozyme patterns found in embryonic tissue and in denervated muscle. BuChE obtained by acrylamide gel electrophoresis along with 16S AchE appears to be a useful biochemical marker of nerve-muscle interactions. |
| doi_str_mv | 10.1007/BF00964958 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_75479954</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>75479954</sourcerecordid><originalsourceid>FETCH-LOGICAL-c282t-2b2a66df7424cc69b49a23e5bbc5faa497adb6c1652c17ec915bc5930f295e83</originalsourceid><addsrcrecordid>eNpF0M1Lw0AQBfBFlFqrF-9CTqJC6ux3Bk-2WBUKXnoPm82GRJJu3G0O_e9NadHTHObH4_EIuaUwpwD6ebECQCVQZmdkSqXmqULg52QKXImUU4RLchXjN8DIGZ2QiWYUlYIpeVnWvm22Lu5cMNElzTbphmhbl_gqKfdxF3xfNzapTXcgMXlYND4VMJfi8ZpcVKaN7uZ0Z2SzetssP9L11_vn8nWdWpaxXcoKZpQqKy2YsFZhIdAw7mRRWFkZI1CbslCWKsks1c4ileMHOVQMpcv4jNwfY_vgf4axad410bq2NVvnh5hrKTSiFCN8OkIbfIzBVXkfms6EfU4hPwyV_w814rtT6lB0rvyjp2X4L3CAYP8</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>75479954</pqid></control><display><type>article</type><title>Cholinesterase in muscle of dystrophic hamsters (Bio-40.54)</title><source>MEDLINE</source><source>SpringerLink (Online service)</source><creator>Henderson, N S ; Tweedle, C D ; Kabara, J J</creator><creatorcontrib>Henderson, N S ; Tweedle, C D ; Kabara, J J</creatorcontrib><description>Isozyme patterns of cholinesterase (ChE) from heart, tongue, and skeletal muscle of normal and dystrophic hamsters are presented. Two principal bands, bands 1 and 2, were evaluated. Band 1 migrates faster towards the anode than does band 2. While bands 1 and 2 stain for AChE and were found in control muscles, only band 2 was stained by a pseudocholinesterase (BuChE) and was decreased in samples from dystrophic hamsters. The decrease in BuChE was most pronounced in dystrophic heart muscle. The low level of BuChE measured for dystrophic animal tissue was similar to isozyme patterns found in embryonic tissue and in denervated muscle. BuChE obtained by acrylamide gel electrophoresis along with 16S AchE appears to be a useful biochemical marker of nerve-muscle interactions.</description><identifier>ISSN: 0364-3190</identifier><identifier>EISSN: 1573-6903</identifier><identifier>DOI: 10.1007/BF00964958</identifier><identifier>PMID: 7219660</identifier><language>eng</language><publisher>United States</publisher><subject>Animals ; Butyrylcholinesterase - metabolism ; Cholinesterases - metabolism ; Cricetinae - metabolism ; Forelimb ; Isoenzymes - metabolism ; Male ; Mesocricetus - metabolism ; Muscles - enzymology ; Muscular Dystrophy, Animal - enzymology ; Muscular Dystrophy, Animal - genetics ; Myocardium - enzymology ; Physical Exertion ; Space life sciences ; Tongue</subject><ispartof>Neurochemical research, 1980-12, Vol.5 (12), p.1221-1230</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c282t-2b2a66df7424cc69b49a23e5bbc5faa497adb6c1652c17ec915bc5930f295e83</citedby><cites>FETCH-LOGICAL-c282t-2b2a66df7424cc69b49a23e5bbc5faa497adb6c1652c17ec915bc5930f295e83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/7219660$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Henderson, N S</creatorcontrib><creatorcontrib>Tweedle, C D</creatorcontrib><creatorcontrib>Kabara, J J</creatorcontrib><title>Cholinesterase in muscle of dystrophic hamsters (Bio-40.54)</title><title>Neurochemical research</title><addtitle>Neurochem Res</addtitle><description>Isozyme patterns of cholinesterase (ChE) from heart, tongue, and skeletal muscle of normal and dystrophic hamsters are presented. Two principal bands, bands 1 and 2, were evaluated. Band 1 migrates faster towards the anode than does band 2. While bands 1 and 2 stain for AChE and were found in control muscles, only band 2 was stained by a pseudocholinesterase (BuChE) and was decreased in samples from dystrophic hamsters. The decrease in BuChE was most pronounced in dystrophic heart muscle. The low level of BuChE measured for dystrophic animal tissue was similar to isozyme patterns found in embryonic tissue and in denervated muscle. BuChE obtained by acrylamide gel electrophoresis along with 16S AchE appears to be a useful biochemical marker of nerve-muscle interactions.</description><subject>Animals</subject><subject>Butyrylcholinesterase - metabolism</subject><subject>Cholinesterases - metabolism</subject><subject>Cricetinae - metabolism</subject><subject>Forelimb</subject><subject>Isoenzymes - metabolism</subject><subject>Male</subject><subject>Mesocricetus - metabolism</subject><subject>Muscles - enzymology</subject><subject>Muscular Dystrophy, Animal - enzymology</subject><subject>Muscular Dystrophy, Animal - genetics</subject><subject>Myocardium - enzymology</subject><subject>Physical Exertion</subject><subject>Space life sciences</subject><subject>Tongue</subject><issn>0364-3190</issn><issn>1573-6903</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1980</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0M1Lw0AQBfBFlFqrF-9CTqJC6ux3Bk-2WBUKXnoPm82GRJJu3G0O_e9NadHTHObH4_EIuaUwpwD6ebECQCVQZmdkSqXmqULg52QKXImUU4RLchXjN8DIGZ2QiWYUlYIpeVnWvm22Lu5cMNElzTbphmhbl_gqKfdxF3xfNzapTXcgMXlYND4VMJfi8ZpcVKaN7uZ0Z2SzetssP9L11_vn8nWdWpaxXcoKZpQqKy2YsFZhIdAw7mRRWFkZI1CbslCWKsks1c4ileMHOVQMpcv4jNwfY_vgf4axad410bq2NVvnh5hrKTSiFCN8OkIbfIzBVXkfms6EfU4hPwyV_w814rtT6lB0rvyjp2X4L3CAYP8</recordid><startdate>198012</startdate><enddate>198012</enddate><creator>Henderson, N S</creator><creator>Tweedle, C D</creator><creator>Kabara, J J</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198012</creationdate><title>Cholinesterase in muscle of dystrophic hamsters (Bio-40.54)</title><author>Henderson, N S ; Tweedle, C D ; Kabara, J J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c282t-2b2a66df7424cc69b49a23e5bbc5faa497adb6c1652c17ec915bc5930f295e83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1980</creationdate><topic>Animals</topic><topic>Butyrylcholinesterase - metabolism</topic><topic>Cholinesterases - metabolism</topic><topic>Cricetinae - metabolism</topic><topic>Forelimb</topic><topic>Isoenzymes - metabolism</topic><topic>Male</topic><topic>Mesocricetus - metabolism</topic><topic>Muscles - enzymology</topic><topic>Muscular Dystrophy, Animal - enzymology</topic><topic>Muscular Dystrophy, Animal - genetics</topic><topic>Myocardium - enzymology</topic><topic>Physical Exertion</topic><topic>Space life sciences</topic><topic>Tongue</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Henderson, N S</creatorcontrib><creatorcontrib>Tweedle, C D</creatorcontrib><creatorcontrib>Kabara, J J</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neurochemical research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Henderson, N S</au><au>Tweedle, C D</au><au>Kabara, J J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cholinesterase in muscle of dystrophic hamsters (Bio-40.54)</atitle><jtitle>Neurochemical research</jtitle><addtitle>Neurochem Res</addtitle><date>1980-12</date><risdate>1980</risdate><volume>5</volume><issue>12</issue><spage>1221</spage><epage>1230</epage><pages>1221-1230</pages><issn>0364-3190</issn><eissn>1573-6903</eissn><abstract>Isozyme patterns of cholinesterase (ChE) from heart, tongue, and skeletal muscle of normal and dystrophic hamsters are presented. Two principal bands, bands 1 and 2, were evaluated. Band 1 migrates faster towards the anode than does band 2. While bands 1 and 2 stain for AChE and were found in control muscles, only band 2 was stained by a pseudocholinesterase (BuChE) and was decreased in samples from dystrophic hamsters. The decrease in BuChE was most pronounced in dystrophic heart muscle. The low level of BuChE measured for dystrophic animal tissue was similar to isozyme patterns found in embryonic tissue and in denervated muscle. BuChE obtained by acrylamide gel electrophoresis along with 16S AchE appears to be a useful biochemical marker of nerve-muscle interactions.</abstract><cop>United States</cop><pmid>7219660</pmid><doi>10.1007/BF00964958</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0364-3190 |
| ispartof | Neurochemical research, 1980-12, Vol.5 (12), p.1221-1230 |
| issn | 0364-3190 1573-6903 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_75479954 |
| source | MEDLINE; SpringerLink (Online service) |
| subjects | Animals Butyrylcholinesterase - metabolism Cholinesterases - metabolism Cricetinae - metabolism Forelimb Isoenzymes - metabolism Male Mesocricetus - metabolism Muscles - enzymology Muscular Dystrophy, Animal - enzymology Muscular Dystrophy, Animal - genetics Myocardium - enzymology Physical Exertion Space life sciences Tongue |
| title | Cholinesterase in muscle of dystrophic hamsters (Bio-40.54) |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T07%3A03%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Cholinesterase%20in%20muscle%20of%20dystrophic%20hamsters%20(Bio-40.54)&rft.jtitle=Neurochemical%20research&rft.au=Henderson,%20N%20S&rft.date=1980-12&rft.volume=5&rft.issue=12&rft.spage=1221&rft.epage=1230&rft.pages=1221-1230&rft.issn=0364-3190&rft.eissn=1573-6903&rft_id=info:doi/10.1007/BF00964958&rft_dat=%3Cproquest_cross%3E75479954%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=75479954&rft_id=info:pmid/7219660&rfr_iscdi=true |