Antitumor activity of L-canavanine against L1210 murine leukemia

We have made a preliminary assessment of the antitumor activity of the arginine analog, L-canavanine, in leukemic mice. This analog is known to substitute for arginine in protein biosynthesis in many prokaryotic and eukaryotic systems. Previous studies with cells grown in vitro indicated that canava...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 1980-03, Vol.40 (3), p.535-537
Hauptverfasser:	Green, M H, Brooks, T L, Mendelsohn, J, Howell, S B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Canavanine - metabolism Canavanine - therapeutic use DNA, Neoplasm - biosynthesis Leukemia L1210 - drug therapy Metabolic Clearance Rate Mice
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