Finite element modeling of the growth plate in a detailed spine model
Very few computer models of the spine integrate vertebral growth plates to investigate their mechanical behavior and potential impacts on bone growth. An approach was developed to generate a finite element (FE) model of the lumbar spine and their connective tissues including the growth plate, which...
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| Veröffentlicht in: | Medical & biological engineering & computing 2007-10, Vol.45 (10), p.977-988 |
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| creator | Sylvestre, Pierre-Luc Villemure, Isabelle Aubin, Carl-Eric |
| description | Very few computer models of the spine integrate vertebral growth plates to investigate their mechanical behavior and potential impacts on bone growth. An approach was developed to generate a finite element (FE) model of the lumbar spine and their connective tissues including the growth plate, which allowed a personalization of the geometry based on patients' bi-planar radiographs. The geometrical validation was performed by deforming meshed vertebrae to reference vertebral specimens and comparing geometrical indices. No significant difference was found between the measured parameters, with errors under 1% in 83% of the geometrical parameters. Mechanical validation was done by simulating loading cases on a functional unit representing experimental testing on cadaveric spines. The flexibility of the functional unit remained between expected ranges of motion, but was more linear than experimental data. The mechanical behavior of the growth plate was evaluated under various loading cases: greater stresses were located in the proliferative zone for the different spinal loading cases tested. This modeling approach is a useful tool to study the effect of mechanical stresses on bone growth. |
| doi_str_mv | 10.1007/s11517-007-0220-z |
| format | Article |
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An approach was developed to generate a finite element (FE) model of the lumbar spine and their connective tissues including the growth plate, which allowed a personalization of the geometry based on patients' bi-planar radiographs. The geometrical validation was performed by deforming meshed vertebrae to reference vertebral specimens and comparing geometrical indices. No significant difference was found between the measured parameters, with errors under 1% in 83% of the geometrical parameters. Mechanical validation was done by simulating loading cases on a functional unit representing experimental testing on cadaveric spines. The flexibility of the functional unit remained between expected ranges of motion, but was more linear than experimental data. The mechanical behavior of the growth plate was evaluated under various loading cases: greater stresses were located in the proliferative zone for the different spinal loading cases tested. 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This modeling approach is a useful tool to study the effect of mechanical stresses on bone growth.</description><subject>Finite Element Analysis</subject><subject>Growth Plate - anatomy & histology</subject><subject>Growth Plate - diagnostic imaging</subject><subject>Growth Plate - physiology</subject><subject>Hierarchies</subject><subject>Humans</subject><subject>Imaging, Three-Dimensional</subject><subject>Intervertebral Disc - anatomy & histology</subject><subject>Ligaments - anatomy & histology</subject><subject>Lumbar Vertebrae</subject><subject>Models, Anatomic</subject><subject>Studies</subject><subject>Tomography, X-Ray Computed</subject><subject>Weight-Bearing</subject><issn>0140-0118</issn><issn>1741-0444</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kU9Lw0AQxRdRbK1-AC-yeNBTdGZ3s5scpbQqFLzoeUmykzYlf2o2Reynd0sLggdP8w6_95iZx9g1wgMCmEePGKOJgoxACIh2J2yMRmEESqlTNgZUEAFiMmIX3q8BBMZCnbMRGp2YOIExm82rthqIU00NtQNvOkd11S55V_JhRXzZd1_Dim_qLEBVyzPuaMiqmhz3m6qlg-GSnZVZ7enqOCfsYz57n75Ei7fn1-nTIipknAyRzIRxKi0V5kaLRKqCUOY5pKl0jkyeYIEFSJRGKu10ashkKFMohVYuhVxO2P0hd9N3n1vyg20qX1BdZy11W29NrGKdCIWBvPuXDJRGATKAt3_Adbft23CF1SpsqUXYbsLwABV9531Ppd30VZP13xbB7quwhyrsXu6rsLvguTkGb_OG3K_j-Hv5A_Bmgds</recordid><startdate>20071001</startdate><enddate>20071001</enddate><creator>Sylvestre, Pierre-Luc</creator><creator>Villemure, Isabelle</creator><creator>Aubin, Carl-Eric</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7SC</scope><scope>7TB</scope><scope>7TS</scope><scope>7WY</scope><scope>7WZ</scope><scope>7X7</scope><scope>7XB</scope><scope>87Z</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AL</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FL</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BEZIV</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FRNLG</scope><scope>FYUFA</scope><scope>F~G</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>JQ2</scope><scope>K60</scope><scope>K6~</scope><scope>K7-</scope><scope>K9.</scope><scope>KB0</scope><scope>L.-</scope><scope>L7M</scope><scope>LK8</scope><scope>L~C</scope><scope>L~D</scope><scope>M0C</scope><scope>M0N</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQBIZ</scope><scope>PQBZA</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>7QO</scope><scope>7QP</scope></search><sort><creationdate>20071001</creationdate><title>Finite element modeling of the growth plate in a detailed spine model</title><author>Sylvestre, Pierre-Luc ; Villemure, Isabelle ; Aubin, Carl-Eric</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c358t-3a27d49f41b762834ce13bb0993dde7b81c1c03137346d697e7a1390f264d90b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Finite Element Analysis</topic><topic>Growth Plate - anatomy & histology</topic><topic>Growth Plate - diagnostic imaging</topic><topic>Growth Plate - physiology</topic><topic>Hierarchies</topic><topic>Humans</topic><topic>Imaging, Three-Dimensional</topic><topic>Intervertebral Disc - anatomy & histology</topic><topic>Ligaments - anatomy & histology</topic><topic>Lumbar Vertebrae</topic><topic>Models, Anatomic</topic><topic>Studies</topic><topic>Tomography, X-Ray Computed</topic><topic>Weight-Bearing</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sylvestre, Pierre-Luc</creatorcontrib><creatorcontrib>Villemure, Isabelle</creatorcontrib><creatorcontrib>Aubin, Carl-Eric</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Computer and Information Systems Abstracts</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Physical Education Index</collection><collection>ABI/INFORM Collection</collection><collection>ABI/INFORM Global (PDF only)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ABI/INFORM Global (Alumni Edition)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>Computing Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ABI/INFORM Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Business Premium Collection</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Business Premium Collection (Alumni)</collection><collection>Health Research Premium Collection</collection><collection>ABI/INFORM Global (Corporate)</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Computer Science Collection</collection><collection>ProQuest Business Collection (Alumni Edition)</collection><collection>ProQuest Business Collection</collection><collection>Computer Science Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ABI/INFORM Professional Advanced</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>ProQuest Biological Science Collection</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>ABI/INFORM Global</collection><collection>Computing Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Business</collection><collection>ProQuest One Business (Alumni)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium & Calcified Tissue Abstracts</collection><jtitle>Medical & biological engineering & computing</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sylvestre, Pierre-Luc</au><au>Villemure, Isabelle</au><au>Aubin, Carl-Eric</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Finite element modeling of the growth plate in a detailed spine model</atitle><jtitle>Medical & biological engineering & computing</jtitle><addtitle>Med Biol Eng Comput</addtitle><date>2007-10-01</date><risdate>2007</risdate><volume>45</volume><issue>10</issue><spage>977</spage><epage>988</epage><pages>977-988</pages><issn>0140-0118</issn><eissn>1741-0444</eissn><abstract>Very few computer models of the spine integrate vertebral growth plates to investigate their mechanical behavior and potential impacts on bone growth. An approach was developed to generate a finite element (FE) model of the lumbar spine and their connective tissues including the growth plate, which allowed a personalization of the geometry based on patients' bi-planar radiographs. The geometrical validation was performed by deforming meshed vertebrae to reference vertebral specimens and comparing geometrical indices. No significant difference was found between the measured parameters, with errors under 1% in 83% of the geometrical parameters. Mechanical validation was done by simulating loading cases on a functional unit representing experimental testing on cadaveric spines. The flexibility of the functional unit remained between expected ranges of motion, but was more linear than experimental data. The mechanical behavior of the growth plate was evaluated under various loading cases: greater stresses were located in the proliferative zone for the different spinal loading cases tested. This modeling approach is a useful tool to study the effect of mechanical stresses on bone growth.</abstract><cop>United States</cop><pub>Springer Nature B.V</pub><pmid>17687580</pmid><doi>10.1007/s11517-007-0220-z</doi><tpages>12</tpages></addata></record> |
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| source | MEDLINE; Business Source Complete; SpringerLink Journals - AutoHoldings |
| subjects | Finite Element Analysis Growth Plate - anatomy & histology Growth Plate - diagnostic imaging Growth Plate - physiology Hierarchies Humans Imaging, Three-Dimensional Intervertebral Disc - anatomy & histology Ligaments - anatomy & histology Lumbar Vertebrae Models, Anatomic Studies Tomography, X-Ray Computed Weight-Bearing |
| title | Finite element modeling of the growth plate in a detailed spine model |
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