Changes in metabolic-related variables during chronic morphine treatment

To reveal neuroendocrine/neurochemical changes that are responsible for the robust metabolic alterations seen during chronic morphine treatment we followed hormonal-, transcriptional- and behavioral changes during chronic morphine administration in adult male Wistar rats. Animals were implanted with...

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Veröffentlicht in:	Neurochemistry international 2010-10, Vol.57 (3), p.323-330
Hauptverfasser:	Ferenczi, Szilamér, Núñez, Cristina, Pintér-Kübler, Bernadett, Földes, Anna, Martín, Fátima, Ladnyánszky Márkus, Vera, Milanés, M. Victoria, Kovács, Krisztina J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adiponectin Adipose Tissue, White - drug effects Adipose Tissue, White - metabolism Analgesics Analgesics, Opioid - pharmacology Animals Behavior, Animal - drug effects Biological and medical sciences Blood Glucose - metabolism Brain Stem - drug effects Brain Stem - metabolism CART DNA Primers Energy Metabolism - drug effects Feeding behavior Feeding Behavior - drug effects FosB Fundamental and applied biological sciences. Psychology Hormones - metabolism Hypothalamus - drug effects Hypothalamus - metabolism Immunohistochemistry Insulin Leptin Male Medical sciences Metabolism - drug effects Morphine - pharmacology Neuropeptides - biosynthesis Neuropeptides - genetics Neuropharmacology NPY Pharmacology. Drug treatments Proto-Oncogene Proteins c-fos - biosynthesis Rats Rats, Wistar Reverse Transcriptase Polymerase Chain Reaction Vertebrates: nervous system and sense organs Weight Gain - drug effects
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