Protection of pregnant mice, fetuses and neonates from lethality of H5N1 influenza viruses by maternal vaccination

Abstract The highly pathogenic H5N1 influenza viruses are one of candidates for the next pandemic. Information on protective immunity for pregnant animals by vaccination against the H5N1 influenza virus is limited. Here, we show that the immunization of pregnant mice with inactivated H5N1 influenza...

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Veröffentlicht in:	Vaccine 2010-04, Vol.28 (17), p.2957-2964
Hauptverfasser:	Hwang, Seon Do, Shin, Jin Soo, Ku, Keun Bon, Kim, Hyun Soo, Cho, Sung Whan, Seo, Sang Heui
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Animals, Newborn Antibodies, Viral - analysis Antibodies, Viral - blood Applied microbiology Avian flu Biological and medical sciences Blood - immunology Cloning Cross Protection Disease control Female Fetus Fetuses Fundamental and applied biological sciences. Psychology H5N1 Immunization Immunization, Secondary - methods Immunoglobulin G - analysis Immunoglobulin G - blood Infants Influenza A Virus, H5N1 Subtype - immunology Influenza Vaccines - immunology Influenza virus Lung - immunology Mice Mice, Inbred BALB C Microbiology Miscellaneous Mortality Myocardium - immunology Neonates Orthomyxoviridae Infections - prevention & control Pandemics Plasmids Pregnancy Rectum - immunology Studies Survival Analysis Time Factors Vaccination - methods Vaccine Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) Vaccines, Inactivated - immunology Virology Viruses Womens health
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