Value of multidetector-row computed tomography in the preoperative T and N staging of gastric carcinoma: A large-scale Chinese study
Objectives To investigate the value of multidetector‐row computed tomography (MDCT) in the preoperative T and N staging of gastric carcinoma and to further investigate the clinicopathological factors affecting the diagnostic accuracy. Methods Seven hundred ninety gastric carcinoma patients underwent...
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| Veröffentlicht in: | Journal of surgical oncology 2009-09, Vol.100 (3), p.205-214 |
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| container_title | Journal of surgical oncology |
| container_volume | 100 |
| creator | Yan, Chao Zhu, Zheng-Gang Yan, Min Zhang, Huan Pan, Zi-Lai Chen, Jun Xiang, Min Chen, Ming-Min Liu, Bing-Ya Yin, Hao-Ran Lin, Yan-Zhen |
| description | Objectives
To investigate the value of multidetector‐row computed tomography (MDCT) in the preoperative T and N staging of gastric carcinoma and to further investigate the clinicopathological factors affecting the diagnostic accuracy.
Methods
Seven hundred ninety gastric carcinoma patients underwent preoperative MDCT examination. The results of MDCT were compared with surgical and pathological findings.
Results
Early gastric carcinoma patients whose primary tumor was detected by MDCT had higher incidence of lymph node metastasis, larger tumor size, and deeper invasion. The overall accuracy of MDCT in determining T stage of gastric carcinoma was 73.80% (T1 45.93%, T2 53.03%, T3 86.49%, and T4 85.79%). The overall accuracy of MDCT in preoperative N staging was 75.22% (N0 76.17%, N1 68.81%, and N2 80.63%). The overall diagnostic sensitivity, specificity, and accuracy of MDCT for determining lymph node metastasis was 86.26%, 76.17%, and 82.09%, respectively. Multivariate analysis showed that the diagnostic sensitivity of MDCT in determining lymph node metastasis related with tumor size, N stage, and number of metastatic lymph nodes.
Conclusions
The clinical value of MDCT in the preoperative T and N staging of gastric carcinoma is relatively high. MDCT can be the first choice for the preoperative evaluation of patients with gastric carcinoma. J. Surg. Oncol. 2009;100:205–214. © 2009 Wiley‐Liss, Inc. |
| doi_str_mv | 10.1002/jso.21316 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_754562915</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67579534</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3936-48d1d21e2d0f90a8df3889bb050f7d4ab11ecc8f10c357fb8d4a008f96f6081b3</originalsourceid><addsrcrecordid>eNp9kc1u1DAURi1ERYfCghdAXlGxSGvn12ZXjWihjFpUBlhajn2dcUniYDuU2fPguMwAK1hZuj7f0dX9EHpGyQklJD-9De4kpwWtH6AFJbzOOOHsIVqkvzwrG04O0eMQbgkhnNflI3RIeVUQmpcL9OOT7GfAzuBh7qPVEEFF5zPv7rBywzRH0Di6wXVeTpsttiOOG8CTBzeBl9F-A7zGctT4CocoOzt297JOhuitwkp6ZUc3yFf4DPfSd5AFJXvAy40dIUDKzHr7BB0Y2Qd4un-P0Mfz1-vlm2x1ffF2ebbKVMGLOiuZpjqnkGtiOJFMm4Ix3rakIqbRpWwpBaWYoUQVVWNalmaEMMNrUxNG2-IIHe-8k3dfZwhRDDYo6Hs5gpuDaKqyqnNOq0S--C9ZN1WTblgm8OUOVN6F4MGIydtB-q2gRNyXI1I54lc5iX2-l87tAPovuW8jAac74M72sP23SVx-uP6tzHYJGyJ8_5OQ_ktasWgq8fnqQtyc37B35eq9WBc_ARPiqcQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67579534</pqid></control><display><type>article</type><title>Value of multidetector-row computed tomography in the preoperative T and N staging of gastric carcinoma: A large-scale Chinese study</title><source>Wiley-Blackwell Journals</source><source>MEDLINE</source><creator>Yan, Chao ; Zhu, Zheng-Gang ; Yan, Min ; Zhang, Huan ; Pan, Zi-Lai ; Chen, Jun ; Xiang, Min ; Chen, Ming-Min ; Liu, Bing-Ya ; Yin, Hao-Ran ; Lin, Yan-Zhen</creator><creatorcontrib>Yan, Chao ; Zhu, Zheng-Gang ; Yan, Min ; Zhang, Huan ; Pan, Zi-Lai ; Chen, Jun ; Xiang, Min ; Chen, Ming-Min ; Liu, Bing-Ya ; Yin, Hao-Ran ; Lin, Yan-Zhen</creatorcontrib><description>Objectives
To investigate the value of multidetector‐row computed tomography (MDCT) in the preoperative T and N staging of gastric carcinoma and to further investigate the clinicopathological factors affecting the diagnostic accuracy.
Methods
Seven hundred ninety gastric carcinoma patients underwent preoperative MDCT examination. The results of MDCT were compared with surgical and pathological findings.
Results
Early gastric carcinoma patients whose primary tumor was detected by MDCT had higher incidence of lymph node metastasis, larger tumor size, and deeper invasion. The overall accuracy of MDCT in determining T stage of gastric carcinoma was 73.80% (T1 45.93%, T2 53.03%, T3 86.49%, and T4 85.79%). The overall accuracy of MDCT in preoperative N staging was 75.22% (N0 76.17%, N1 68.81%, and N2 80.63%). The overall diagnostic sensitivity, specificity, and accuracy of MDCT for determining lymph node metastasis was 86.26%, 76.17%, and 82.09%, respectively. Multivariate analysis showed that the diagnostic sensitivity of MDCT in determining lymph node metastasis related with tumor size, N stage, and number of metastatic lymph nodes.
Conclusions
The clinical value of MDCT in the preoperative T and N staging of gastric carcinoma is relatively high. MDCT can be the first choice for the preoperative evaluation of patients with gastric carcinoma. J. Surg. Oncol. 2009;100:205–214. © 2009 Wiley‐Liss, Inc.</description><identifier>ISSN: 0022-4790</identifier><identifier>EISSN: 1096-9098</identifier><identifier>DOI: 10.1002/jso.21316</identifier><identifier>PMID: 19530124</identifier><language>eng</language><publisher>Hoboken: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Carcinoma - pathology ; China ; Female ; Gastrectomy ; Humans ; Lymph Node Excision ; lymph node metastasis ; Lymphatic Metastasis - diagnosis ; Male ; Middle Aged ; Neoplasm Invasiveness ; Neoplasm Staging - methods ; Preoperative Care ; ROC Curve ; Sensitivity and Specificity ; staging ; stomach neoplasms ; Stomach Neoplasms - pathology ; tomography ; Tomography, X-Ray Computed - methods ; X-ray computed</subject><ispartof>Journal of surgical oncology, 2009-09, Vol.100 (3), p.205-214</ispartof><rights>Copyright © 2009 Wiley‐Liss, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3936-48d1d21e2d0f90a8df3889bb050f7d4ab11ecc8f10c357fb8d4a008f96f6081b3</citedby><cites>FETCH-LOGICAL-c3936-48d1d21e2d0f90a8df3889bb050f7d4ab11ecc8f10c357fb8d4a008f96f6081b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjso.21316$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjso.21316$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19530124$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yan, Chao</creatorcontrib><creatorcontrib>Zhu, Zheng-Gang</creatorcontrib><creatorcontrib>Yan, Min</creatorcontrib><creatorcontrib>Zhang, Huan</creatorcontrib><creatorcontrib>Pan, Zi-Lai</creatorcontrib><creatorcontrib>Chen, Jun</creatorcontrib><creatorcontrib>Xiang, Min</creatorcontrib><creatorcontrib>Chen, Ming-Min</creatorcontrib><creatorcontrib>Liu, Bing-Ya</creatorcontrib><creatorcontrib>Yin, Hao-Ran</creatorcontrib><creatorcontrib>Lin, Yan-Zhen</creatorcontrib><title>Value of multidetector-row computed tomography in the preoperative T and N staging of gastric carcinoma: A large-scale Chinese study</title><title>Journal of surgical oncology</title><addtitle>J. Surg. Oncol</addtitle><description>Objectives
To investigate the value of multidetector‐row computed tomography (MDCT) in the preoperative T and N staging of gastric carcinoma and to further investigate the clinicopathological factors affecting the diagnostic accuracy.
Methods
Seven hundred ninety gastric carcinoma patients underwent preoperative MDCT examination. The results of MDCT were compared with surgical and pathological findings.
Results
Early gastric carcinoma patients whose primary tumor was detected by MDCT had higher incidence of lymph node metastasis, larger tumor size, and deeper invasion. The overall accuracy of MDCT in determining T stage of gastric carcinoma was 73.80% (T1 45.93%, T2 53.03%, T3 86.49%, and T4 85.79%). The overall accuracy of MDCT in preoperative N staging was 75.22% (N0 76.17%, N1 68.81%, and N2 80.63%). The overall diagnostic sensitivity, specificity, and accuracy of MDCT for determining lymph node metastasis was 86.26%, 76.17%, and 82.09%, respectively. Multivariate analysis showed that the diagnostic sensitivity of MDCT in determining lymph node metastasis related with tumor size, N stage, and number of metastatic lymph nodes.
Conclusions
The clinical value of MDCT in the preoperative T and N staging of gastric carcinoma is relatively high. MDCT can be the first choice for the preoperative evaluation of patients with gastric carcinoma. J. Surg. Oncol. 2009;100:205–214. © 2009 Wiley‐Liss, Inc.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Carcinoma - pathology</subject><subject>China</subject><subject>Female</subject><subject>Gastrectomy</subject><subject>Humans</subject><subject>Lymph Node Excision</subject><subject>lymph node metastasis</subject><subject>Lymphatic Metastasis - diagnosis</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neoplasm Invasiveness</subject><subject>Neoplasm Staging - methods</subject><subject>Preoperative Care</subject><subject>ROC Curve</subject><subject>Sensitivity and Specificity</subject><subject>staging</subject><subject>stomach neoplasms</subject><subject>Stomach Neoplasms - pathology</subject><subject>tomography</subject><subject>Tomography, X-Ray Computed - methods</subject><subject>X-ray computed</subject><issn>0022-4790</issn><issn>1096-9098</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc1u1DAURi1ERYfCghdAXlGxSGvn12ZXjWihjFpUBlhajn2dcUniYDuU2fPguMwAK1hZuj7f0dX9EHpGyQklJD-9De4kpwWtH6AFJbzOOOHsIVqkvzwrG04O0eMQbgkhnNflI3RIeVUQmpcL9OOT7GfAzuBh7qPVEEFF5zPv7rBywzRH0Di6wXVeTpsttiOOG8CTBzeBl9F-A7zGctT4CocoOzt297JOhuitwkp6ZUc3yFf4DPfSd5AFJXvAy40dIUDKzHr7BB0Y2Qd4un-P0Mfz1-vlm2x1ffF2ebbKVMGLOiuZpjqnkGtiOJFMm4Ix3rakIqbRpWwpBaWYoUQVVWNalmaEMMNrUxNG2-IIHe-8k3dfZwhRDDYo6Hs5gpuDaKqyqnNOq0S--C9ZN1WTblgm8OUOVN6F4MGIydtB-q2gRNyXI1I54lc5iX2-l87tAPovuW8jAac74M72sP23SVx-uP6tzHYJGyJ8_5OQ_ktasWgq8fnqQtyc37B35eq9WBc_ARPiqcQ</recordid><startdate>20090901</startdate><enddate>20090901</enddate><creator>Yan, Chao</creator><creator>Zhu, Zheng-Gang</creator><creator>Yan, Min</creator><creator>Zhang, Huan</creator><creator>Pan, Zi-Lai</creator><creator>Chen, Jun</creator><creator>Xiang, Min</creator><creator>Chen, Ming-Min</creator><creator>Liu, Bing-Ya</creator><creator>Yin, Hao-Ran</creator><creator>Lin, Yan-Zhen</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20090901</creationdate><title>Value of multidetector-row computed tomography in the preoperative T and N staging of gastric carcinoma: A large-scale Chinese study</title><author>Yan, Chao ; Zhu, Zheng-Gang ; Yan, Min ; Zhang, Huan ; Pan, Zi-Lai ; Chen, Jun ; Xiang, Min ; Chen, Ming-Min ; Liu, Bing-Ya ; Yin, Hao-Ran ; Lin, Yan-Zhen</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3936-48d1d21e2d0f90a8df3889bb050f7d4ab11ecc8f10c357fb8d4a008f96f6081b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Carcinoma - pathology</topic><topic>China</topic><topic>Female</topic><topic>Gastrectomy</topic><topic>Humans</topic><topic>Lymph Node Excision</topic><topic>lymph node metastasis</topic><topic>Lymphatic Metastasis - diagnosis</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neoplasm Invasiveness</topic><topic>Neoplasm Staging - methods</topic><topic>Preoperative Care</topic><topic>ROC Curve</topic><topic>Sensitivity and Specificity</topic><topic>staging</topic><topic>stomach neoplasms</topic><topic>Stomach Neoplasms - pathology</topic><topic>tomography</topic><topic>Tomography, X-Ray Computed - methods</topic><topic>X-ray computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yan, Chao</creatorcontrib><creatorcontrib>Zhu, Zheng-Gang</creatorcontrib><creatorcontrib>Yan, Min</creatorcontrib><creatorcontrib>Zhang, Huan</creatorcontrib><creatorcontrib>Pan, Zi-Lai</creatorcontrib><creatorcontrib>Chen, Jun</creatorcontrib><creatorcontrib>Xiang, Min</creatorcontrib><creatorcontrib>Chen, Ming-Min</creatorcontrib><creatorcontrib>Liu, Bing-Ya</creatorcontrib><creatorcontrib>Yin, Hao-Ran</creatorcontrib><creatorcontrib>Lin, Yan-Zhen</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Journal of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yan, Chao</au><au>Zhu, Zheng-Gang</au><au>Yan, Min</au><au>Zhang, Huan</au><au>Pan, Zi-Lai</au><au>Chen, Jun</au><au>Xiang, Min</au><au>Chen, Ming-Min</au><au>Liu, Bing-Ya</au><au>Yin, Hao-Ran</au><au>Lin, Yan-Zhen</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Value of multidetector-row computed tomography in the preoperative T and N staging of gastric carcinoma: A large-scale Chinese study</atitle><jtitle>Journal of surgical oncology</jtitle><addtitle>J. Surg. Oncol</addtitle><date>2009-09-01</date><risdate>2009</risdate><volume>100</volume><issue>3</issue><spage>205</spage><epage>214</epage><pages>205-214</pages><issn>0022-4790</issn><eissn>1096-9098</eissn><abstract>Objectives
To investigate the value of multidetector‐row computed tomography (MDCT) in the preoperative T and N staging of gastric carcinoma and to further investigate the clinicopathological factors affecting the diagnostic accuracy.
Methods
Seven hundred ninety gastric carcinoma patients underwent preoperative MDCT examination. The results of MDCT were compared with surgical and pathological findings.
Results
Early gastric carcinoma patients whose primary tumor was detected by MDCT had higher incidence of lymph node metastasis, larger tumor size, and deeper invasion. The overall accuracy of MDCT in determining T stage of gastric carcinoma was 73.80% (T1 45.93%, T2 53.03%, T3 86.49%, and T4 85.79%). The overall accuracy of MDCT in preoperative N staging was 75.22% (N0 76.17%, N1 68.81%, and N2 80.63%). The overall diagnostic sensitivity, specificity, and accuracy of MDCT for determining lymph node metastasis was 86.26%, 76.17%, and 82.09%, respectively. Multivariate analysis showed that the diagnostic sensitivity of MDCT in determining lymph node metastasis related with tumor size, N stage, and number of metastatic lymph nodes.
Conclusions
The clinical value of MDCT in the preoperative T and N staging of gastric carcinoma is relatively high. MDCT can be the first choice for the preoperative evaluation of patients with gastric carcinoma. J. Surg. Oncol. 2009;100:205–214. © 2009 Wiley‐Liss, Inc.</abstract><cop>Hoboken</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>19530124</pmid><doi>10.1002/jso.21316</doi><tpages>10</tpages></addata></record> |
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| source | Wiley-Blackwell Journals; MEDLINE |
| subjects | Adolescent Adult Aged Aged, 80 and over Carcinoma - pathology China Female Gastrectomy Humans Lymph Node Excision lymph node metastasis Lymphatic Metastasis - diagnosis Male Middle Aged Neoplasm Invasiveness Neoplasm Staging - methods Preoperative Care ROC Curve Sensitivity and Specificity staging stomach neoplasms Stomach Neoplasms - pathology tomography Tomography, X-Ray Computed - methods X-ray computed |
| title | Value of multidetector-row computed tomography in the preoperative T and N staging of gastric carcinoma: A large-scale Chinese study |
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