Clostridium difficile toxin a therapy for hct 116 human colon cancer in nude mice

Clostridium difficile toxin A was evaluated for an antitumor effect in vivo on HCT 116 human colon carcinoma cells growing subcutaneously in nude mice. A mean reduction in tumor volume of at least 65%, by measurement in three dimensions, was observed in mice who received two 9‐ to 13‐day courses of...

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Veröffentlicht in:	Journal of surgical oncology 1994-11, Vol.57 (3), p.191-195
Hauptverfasser:	Kushnaryov, Vladimir M., Hernandez, Irene, Grossberg, Sidney E., Redlich, Philip N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents antitumor activity Bacterial Toxins Biological and medical sciences C. difficile Clostridium difficile colon cancer Colonic Neoplasms - drug therapy Enterotoxins - therapeutic use Humans Immunotherapy Medical sciences Mice Mice, Nude nude mouse Pharmacology. Drug treatments toxin A Tumor Cells, Cultured
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