The effect of the fiber components cellulose and lignin on experimental colon neoplasia
Sixty Sprague‐Dawley rats were pair‐fed one of three nutritionally identical diets. One diet contained “low‐fiber” (3.8% crude fiber); the others contained “high fiber” (28.7% crude fiber) composed of either cellulose or lignin. Although both “high fiber” diets had similar stool bulking effects, onl...
Gespeichert in:
| Veröffentlicht in: | Journal of surgical oncology 1993-02, Vol.52 (2), p.77-82 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 82 |
|---|---|
| container_issue | 2 |
| container_start_page | 77 |
| container_title | Journal of surgical oncology |
| container_volume | 52 |
| creator | Sloan, David A. Fleiszer, David M. Richards, Geoffrey K. Murray, David Brown, Rea A. |
| description | Sixty Sprague‐Dawley rats were pair‐fed one of three nutritionally identical diets. One diet contained “low‐fiber” (3.8% crude fiber); the others contained “high fiber” (28.7% crude fiber) composed of either cellulose or lignin. Although both “high fiber” diets had similar stool bulking effects, only the cellulose diet was associated with a reduction in 1,2‐dimethylhydrazine (DMH)‐induced colon neoplasms. The cellulose diet was also associated with distinct changes in the gut bacterial profile and with a lowered serum cholesterol. © 1993 Wiley‐Liss, Inc. |
| doi_str_mv | 10.1002/jso.2930520204 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_754562748</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>754562748</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4394-b31568ce3bec02724775c9347cd8c69b2f5bb40bac2355c30deeb6f7ff7280823</originalsourceid><addsrcrecordid>eNqFkM1vEzEQxS0EKqFw5YbkAxKnDbP-XB9RC4WqtKIU9WjZzhi2OOtlvRHtf4-jREGcOI1m5vdmnh4hL1tYtgDs7V3JS2Y4SAYMxCOyaMGoxoDpHpNFBVgjtIGn5FkpdwBgjBJH5KjjndSML8jtzQ-kGCOGmeZI59rF3uNEQ16PecBhLjRgSpuUC1I3rGjqvw_9QPNA8X7EqV9XxqXKpzoaMI_Jld49J0-iSwVf7Osx-fbh_c3Jx-bi6uzTybuLJghuRON5K1UXkHsMwDQTWstguNBh1QVlPIvSewHeBcalDBxWiF5FHaNmHXSMH5M3u7vjlH9tsMx23ZetYVetbIrVUkjFtOgqudyRYcqlTBjtWM276cG2YLdR2hql_RtlFbzan974Na4O-D67un-937sSXIqTG0JfDphQClS7xcwO-90nfPjPU3v-9eofC81O25cZ7w9aN_20SnMt7e3lmT0HcX395fLUfuZ_AEsunB0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>754562748</pqid></control><display><type>article</type><title>The effect of the fiber components cellulose and lignin on experimental colon neoplasia</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Sloan, David A. ; Fleiszer, David M. ; Richards, Geoffrey K. ; Murray, David ; Brown, Rea A.</creator><creatorcontrib>Sloan, David A. ; Fleiszer, David M. ; Richards, Geoffrey K. ; Murray, David ; Brown, Rea A.</creatorcontrib><description>Sixty Sprague‐Dawley rats were pair‐fed one of three nutritionally identical diets. One diet contained “low‐fiber” (3.8% crude fiber); the others contained “high fiber” (28.7% crude fiber) composed of either cellulose or lignin. Although both “high fiber” diets had similar stool bulking effects, only the cellulose diet was associated with a reduction in 1,2‐dimethylhydrazine (DMH)‐induced colon neoplasms. The cellulose diet was also associated with distinct changes in the gut bacterial profile and with a lowered serum cholesterol. © 1993 Wiley‐Liss, Inc.</description><identifier>ISSN: 0022-4790</identifier><identifier>EISSN: 1096-9098</identifier><identifier>DOI: 10.1002/jso.2930520204</identifier><identifier>PMID: 8385723</identifier><identifier>CODEN: JSONAU</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>1,2-Dimethylhydrazine ; Animal tumors. Experimental tumors ; Animals ; Biological and medical sciences ; Carcinogens ; Cellulose - therapeutic use ; Colon - microbiology ; Colonic Neoplasms - chemically induced ; Colonic Neoplasms - diet therapy ; Colonic Neoplasms - microbiology ; dietary fiber ; Dietary Fiber - therapeutic use ; Dimethylhydrazines ; Experimental digestive system and abdominal tumors ; Feces - microbiology ; gut bacteria ; Lignin - therapeutic use ; Medical sciences ; Rats ; Rats, Sprague-Dawley ; Tumors</subject><ispartof>Journal of surgical oncology, 1993-02, Vol.52 (2), p.77-82</ispartof><rights>Copyright © 1993 Wiley‐Liss, Inc., A Wiley Company</rights><rights>1993 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4394-b31568ce3bec02724775c9347cd8c69b2f5bb40bac2355c30deeb6f7ff7280823</citedby><cites>FETCH-LOGICAL-c4394-b31568ce3bec02724775c9347cd8c69b2f5bb40bac2355c30deeb6f7ff7280823</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjso.2930520204$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjso.2930520204$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,778,782,1414,27907,27908,45557,45558</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4660613$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/8385723$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sloan, David A.</creatorcontrib><creatorcontrib>Fleiszer, David M.</creatorcontrib><creatorcontrib>Richards, Geoffrey K.</creatorcontrib><creatorcontrib>Murray, David</creatorcontrib><creatorcontrib>Brown, Rea A.</creatorcontrib><title>The effect of the fiber components cellulose and lignin on experimental colon neoplasia</title><title>Journal of surgical oncology</title><addtitle>J. Surg. Oncol</addtitle><description>Sixty Sprague‐Dawley rats were pair‐fed one of three nutritionally identical diets. One diet contained “low‐fiber” (3.8% crude fiber); the others contained “high fiber” (28.7% crude fiber) composed of either cellulose or lignin. Although both “high fiber” diets had similar stool bulking effects, only the cellulose diet was associated with a reduction in 1,2‐dimethylhydrazine (DMH)‐induced colon neoplasms. The cellulose diet was also associated with distinct changes in the gut bacterial profile and with a lowered serum cholesterol. © 1993 Wiley‐Liss, Inc.</description><subject>1,2-Dimethylhydrazine</subject><subject>Animal tumors. Experimental tumors</subject><subject>Animals</subject><subject>Biological and medical sciences</subject><subject>Carcinogens</subject><subject>Cellulose - therapeutic use</subject><subject>Colon - microbiology</subject><subject>Colonic Neoplasms - chemically induced</subject><subject>Colonic Neoplasms - diet therapy</subject><subject>Colonic Neoplasms - microbiology</subject><subject>dietary fiber</subject><subject>Dietary Fiber - therapeutic use</subject><subject>Dimethylhydrazines</subject><subject>Experimental digestive system and abdominal tumors</subject><subject>Feces - microbiology</subject><subject>gut bacteria</subject><subject>Lignin - therapeutic use</subject><subject>Medical sciences</subject><subject>Rats</subject><subject>Rats, Sprague-Dawley</subject><subject>Tumors</subject><issn>0022-4790</issn><issn>1096-9098</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1993</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkM1vEzEQxS0EKqFw5YbkAxKnDbP-XB9RC4WqtKIU9WjZzhi2OOtlvRHtf4-jREGcOI1m5vdmnh4hL1tYtgDs7V3JS2Y4SAYMxCOyaMGoxoDpHpNFBVgjtIGn5FkpdwBgjBJH5KjjndSML8jtzQ-kGCOGmeZI59rF3uNEQ16PecBhLjRgSpuUC1I3rGjqvw_9QPNA8X7EqV9XxqXKpzoaMI_Jld49J0-iSwVf7Osx-fbh_c3Jx-bi6uzTybuLJghuRON5K1UXkHsMwDQTWstguNBh1QVlPIvSewHeBcalDBxWiF5FHaNmHXSMH5M3u7vjlH9tsMx23ZetYVetbIrVUkjFtOgqudyRYcqlTBjtWM276cG2YLdR2hql_RtlFbzan974Na4O-D67un-937sSXIqTG0JfDphQClS7xcwO-90nfPjPU3v-9eofC81O25cZ7w9aN_20SnMt7e3lmT0HcX395fLUfuZ_AEsunB0</recordid><startdate>199302</startdate><enddate>199302</enddate><creator>Sloan, David A.</creator><creator>Fleiszer, David M.</creator><creator>Richards, Geoffrey K.</creator><creator>Murray, David</creator><creator>Brown, Rea A.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7T7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>199302</creationdate><title>The effect of the fiber components cellulose and lignin on experimental colon neoplasia</title><author>Sloan, David A. ; Fleiszer, David M. ; Richards, Geoffrey K. ; Murray, David ; Brown, Rea A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4394-b31568ce3bec02724775c9347cd8c69b2f5bb40bac2355c30deeb6f7ff7280823</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>1,2-Dimethylhydrazine</topic><topic>Animal tumors. Experimental tumors</topic><topic>Animals</topic><topic>Biological and medical sciences</topic><topic>Carcinogens</topic><topic>Cellulose - therapeutic use</topic><topic>Colon - microbiology</topic><topic>Colonic Neoplasms - chemically induced</topic><topic>Colonic Neoplasms - diet therapy</topic><topic>Colonic Neoplasms - microbiology</topic><topic>dietary fiber</topic><topic>Dietary Fiber - therapeutic use</topic><topic>Dimethylhydrazines</topic><topic>Experimental digestive system and abdominal tumors</topic><topic>Feces - microbiology</topic><topic>gut bacteria</topic><topic>Lignin - therapeutic use</topic><topic>Medical sciences</topic><topic>Rats</topic><topic>Rats, Sprague-Dawley</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sloan, David A.</creatorcontrib><creatorcontrib>Fleiszer, David M.</creatorcontrib><creatorcontrib>Richards, Geoffrey K.</creatorcontrib><creatorcontrib>Murray, David</creatorcontrib><creatorcontrib>Brown, Rea A.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Journal of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sloan, David A.</au><au>Fleiszer, David M.</au><au>Richards, Geoffrey K.</au><au>Murray, David</au><au>Brown, Rea A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of the fiber components cellulose and lignin on experimental colon neoplasia</atitle><jtitle>Journal of surgical oncology</jtitle><addtitle>J. Surg. Oncol</addtitle><date>1993-02</date><risdate>1993</risdate><volume>52</volume><issue>2</issue><spage>77</spage><epage>82</epage><pages>77-82</pages><issn>0022-4790</issn><eissn>1096-9098</eissn><coden>JSONAU</coden><abstract>Sixty Sprague‐Dawley rats were pair‐fed one of three nutritionally identical diets. One diet contained “low‐fiber” (3.8% crude fiber); the others contained “high fiber” (28.7% crude fiber) composed of either cellulose or lignin. Although both “high fiber” diets had similar stool bulking effects, only the cellulose diet was associated with a reduction in 1,2‐dimethylhydrazine (DMH)‐induced colon neoplasms. The cellulose diet was also associated with distinct changes in the gut bacterial profile and with a lowered serum cholesterol. © 1993 Wiley‐Liss, Inc.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>8385723</pmid><doi>10.1002/jso.2930520204</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-4790 |
| ispartof | Journal of surgical oncology, 1993-02, Vol.52 (2), p.77-82 |
| issn | 0022-4790 1096-9098 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_754562748 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | 1,2-Dimethylhydrazine Animal tumors. Experimental tumors Animals Biological and medical sciences Carcinogens Cellulose - therapeutic use Colon - microbiology Colonic Neoplasms - chemically induced Colonic Neoplasms - diet therapy Colonic Neoplasms - microbiology dietary fiber Dietary Fiber - therapeutic use Dimethylhydrazines Experimental digestive system and abdominal tumors Feces - microbiology gut bacteria Lignin - therapeutic use Medical sciences Rats Rats, Sprague-Dawley Tumors |
| title | The effect of the fiber components cellulose and lignin on experimental colon neoplasia |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T18%3A52%3A52IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20effect%20of%20the%20fiber%20components%20cellulose%20and%20lignin%20on%20experimental%20colon%20neoplasia&rft.jtitle=Journal%20of%20surgical%20oncology&rft.au=Sloan,%20David%20A.&rft.date=1993-02&rft.volume=52&rft.issue=2&rft.spage=77&rft.epage=82&rft.pages=77-82&rft.issn=0022-4790&rft.eissn=1096-9098&rft.coden=JSONAU&rft_id=info:doi/10.1002/jso.2930520204&rft_dat=%3Cproquest_cross%3E754562748%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=754562748&rft_id=info:pmid/8385723&rfr_iscdi=true |