Analysis of complement receptor Type 1 expression on red blood cells in negative phenotypes of the Knops blood group system, according to CR1 gene allotype polymorphisms

BACKGROUND: The KN blood group system, which consists of nine antigen specificities, is located on complement receptor Type 1 (CR1/CD35). CR1, a complement regulatory protein, acts as a vehicle for immune complex clearance. CR1 exhibits a red blood cell (RBC) density polymorphism. CR1 sites on RBCs...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 2010-07, Vol.50 (7), p.1435-1443
Hauptverfasser:	Pham, Bach-Nga, Kisserli, Aymric, Donvito, Béatrice, Duret, Valérie, Reveil, Brigitte, Tabary, Thierry, Le Pennec, Pierre-Yves, Peyrard, Thierry, Rouger, Philippe, Cohen, Jacques H.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood Group Antigens - genetics Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Bone marrow, stem cells transplantation. Graft versus host reaction Erythrocytes - chemistry Humans Medical sciences Phenotype Polymorphism, Genetic Receptors, Complement 3b - analysis Receptors, Complement 3b - genetics Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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