KIAA1718 is a histone demethylase that erases repressive histone methyl marks

The methylation states of histone lysine residues are regarded as significant epigenetic marks governing transcriptional regulation. A number of histone demethylases containing a jumonji C (JmjC) domain have been recognized; however, their properties remain to be investigated. Here, we show that KIA...

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Veröffentlicht in:	Genes to cells : devoted to molecular & cellular mechanisms 2010-08, Vol.15 (8), p.867-873
Hauptverfasser:	Yokoyama, Atsushi, Okuno, Yosuke, Chikanishi, Toshihiro, Hashiba, Waka, Sekine, Hiroki, Fujiki, Ryoji, Kato, Shigeaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cells, Cultured Chromatin epigenetics Gene regulation Histone Demethylases - chemistry Histone Demethylases - metabolism Histones Histones - metabolism Humans Lysine Lysine - metabolism Methylation Mice Purification Transcription activation
Online-Zugang:	Volltext
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