Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells

Medulloblastoma is an aggressive primary brain tumor that arises in the cerebellum of children and young adults. The Sonic Hedgehog (Shh) signaling pathway that plays important roles in the pathology of this aggressive disease is a promising therapeutic target. In the present report we have shown th...

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Veröffentlicht in:Molecular carcinogenesis 2010-03, Vol.49 (3), p.302-314
Hauptverfasser: Elamin, Maha H., Shinwari, Zakia, Hendrayani, Siti-Faujiah, Al-Hindi, Hindi, Al-Shail, Essam, khafaga, Yasser, Al-kofide, Amani, Aboussekhra, Abdelilah
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