Neurodegenerative effects of monopolar electrocauterization on spinal ganglia in lumbar disc surgery
Monopolar electrocauterization (MEC) is widely used in spine surgery however electrical currents are hazardous for neural tissues, such as the spinal ganglia sited in the intervertebral foramina. We aimed to investigate the effects of MEC on spinal ganglia. Fifteen male hybrid rabbits were included...
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| Veröffentlicht in: | Acta neurochirurgica 2004-10, Vol.146 (10), p.1125-1129 |
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| creator | Aydin, M D Dane, S Gundogdu, C Gursan, N |
| description | Monopolar electrocauterization (MEC) is widely used in spine surgery however electrical currents are hazardous for neural tissues, such as the spinal ganglia sited in the intervertebral foramina. We aimed to investigate the effects of MEC on spinal ganglia.
Fifteen male hybrid rabbits were included in the study. Three of the animals were used to analyze the findings regarding spinal ganglia without operation. The remaining animals underwent L4-5 disc surgery. For intra-operative facet denervation MEC was used for half of the animals. After one month, all animals were sacrificed and L5 spinal ganglia were removed for histopathological examination. The number and morphological changes of neurons in spinal ganglia were examined.
The mean number of live neurons was 22610 in non-operated rabbits; 21617 in the non-MEC group and 16692 in the MEC group. Neuronal degeneration was more prominent in the MEC group than in the non-MEC group.
MEC used during spine surgery may be injurious to spinal ganglia and should be used with caution. |
| doi_str_mv | 10.1007/s00701-004-0300-x |
| format | Article |
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Fifteen male hybrid rabbits were included in the study. Three of the animals were used to analyze the findings regarding spinal ganglia without operation. The remaining animals underwent L4-5 disc surgery. For intra-operative facet denervation MEC was used for half of the animals. After one month, all animals were sacrificed and L5 spinal ganglia were removed for histopathological examination. The number and morphological changes of neurons in spinal ganglia were examined.
The mean number of live neurons was 22610 in non-operated rabbits; 21617 in the non-MEC group and 16692 in the MEC group. Neuronal degeneration was more prominent in the MEC group than in the non-MEC group.
MEC used during spine surgery may be injurious to spinal ganglia and should be used with caution.</description><identifier>ISSN: 0001-6268</identifier><identifier>EISSN: 0942-0940</identifier><identifier>DOI: 10.1007/s00701-004-0300-x</identifier><identifier>PMID: 15744848</identifier><language>eng</language><publisher>Austria: Springer Nature B.V</publisher><subject>Animals ; Blood Vessels - enzymology ; Blood Vessels - pathology ; Blood Vessels - physiopathology ; Cicatrix - etiology ; Cicatrix - pathology ; Cicatrix - physiopathology ; Denervation - adverse effects ; Disease Models, Animal ; Diskectomy - adverse effects ; Electrocoagulation - adverse effects ; Ganglia, Spinal - anatomy & histology ; Ganglia, Spinal - injuries ; Ischemia - etiology ; Ischemia - pathology ; Ischemia - physiopathology ; Lumbar Vertebrae - anatomy & histology ; Lumbar Vertebrae - surgery ; Male ; Nerve Degeneration - etiology ; Nerve Degeneration - pathology ; Nerve Degeneration - physiopathology ; Nerve Fibers, Myelinated - pathology ; Nerve Fibers, Myelinated - physiology ; Neurons, Afferent - pathology ; Neurons, Afferent - physiology ; Neurosurgical Procedures - adverse effects ; Postoperative Complications - etiology ; Postoperative Complications - physiopathology ; Postoperative Complications - prevention & control ; Rabbits ; Spine ; Zygapophyseal Joint - injuries ; Zygapophyseal Joint - innervation</subject><ispartof>Acta neurochirurgica, 2004-10, Vol.146 (10), p.1125-1129</ispartof><rights>Springer-Verlag/Wien 2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c356t-f721441d6fa6b84802bcc4166e0d31b57e86ea47d5cca528edddb330ce047fa73</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15744848$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Aydin, M D</creatorcontrib><creatorcontrib>Dane, S</creatorcontrib><creatorcontrib>Gundogdu, C</creatorcontrib><creatorcontrib>Gursan, N</creatorcontrib><title>Neurodegenerative effects of monopolar electrocauterization on spinal ganglia in lumbar disc surgery</title><title>Acta neurochirurgica</title><addtitle>Acta Neurochir (Wien)</addtitle><description>Monopolar electrocauterization (MEC) is widely used in spine surgery however electrical currents are hazardous for neural tissues, such as the spinal ganglia sited in the intervertebral foramina. We aimed to investigate the effects of MEC on spinal ganglia.
Fifteen male hybrid rabbits were included in the study. Three of the animals were used to analyze the findings regarding spinal ganglia without operation. The remaining animals underwent L4-5 disc surgery. For intra-operative facet denervation MEC was used for half of the animals. After one month, all animals were sacrificed and L5 spinal ganglia were removed for histopathological examination. The number and morphological changes of neurons in spinal ganglia were examined.
The mean number of live neurons was 22610 in non-operated rabbits; 21617 in the non-MEC group and 16692 in the MEC group. Neuronal degeneration was more prominent in the MEC group than in the non-MEC group.
MEC used during spine surgery may be injurious to spinal ganglia and should be used with caution.</description><subject>Animals</subject><subject>Blood Vessels - enzymology</subject><subject>Blood Vessels - pathology</subject><subject>Blood Vessels - physiopathology</subject><subject>Cicatrix - etiology</subject><subject>Cicatrix - pathology</subject><subject>Cicatrix - physiopathology</subject><subject>Denervation - adverse effects</subject><subject>Disease Models, Animal</subject><subject>Diskectomy - adverse effects</subject><subject>Electrocoagulation - adverse effects</subject><subject>Ganglia, Spinal - anatomy & histology</subject><subject>Ganglia, Spinal - injuries</subject><subject>Ischemia - etiology</subject><subject>Ischemia - pathology</subject><subject>Ischemia - physiopathology</subject><subject>Lumbar Vertebrae - anatomy & histology</subject><subject>Lumbar Vertebrae - surgery</subject><subject>Male</subject><subject>Nerve Degeneration - etiology</subject><subject>Nerve Degeneration - pathology</subject><subject>Nerve Degeneration - physiopathology</subject><subject>Nerve Fibers, Myelinated - pathology</subject><subject>Nerve Fibers, Myelinated - physiology</subject><subject>Neurons, Afferent - pathology</subject><subject>Neurons, Afferent - physiology</subject><subject>Neurosurgical Procedures - adverse effects</subject><subject>Postoperative Complications - etiology</subject><subject>Postoperative Complications - physiopathology</subject><subject>Postoperative Complications - prevention & control</subject><subject>Rabbits</subject><subject>Spine</subject><subject>Zygapophyseal Joint - injuries</subject><subject>Zygapophyseal Joint - innervation</subject><issn>0001-6268</issn><issn>0942-0940</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kUtLxDAUhYMovn-AGwkudFW9aV6dpQy-QHSj65Amt0OlbcakFfXXm2EGBBdCuLlJvnO44RBywuCSAeirlAuwAkAUwAGKzy2yDzNRFrnAdu4hv6pSVXvkIKW3fCq14Ltkj0ktRCWqfeKfcIrB4wIHjHZsP5Bi06AbEw0N7cMQlqGzkWKX72Jwdhoxtt-ZDAPNKy3bwXZ0YYdF11raDrSb-joLfJscTVNcYPw6IjuN7RIeb_ZD8np78zK_Lx6f7x7m14-F41KNRaNLJgTzqrGqztNBWTsnmFIInrNaaqwUWqG9dM7KskLvfc05OAShG6v5IblY-y5jeJ8wjabPU2DX2QHDlIyWQko5Yyvy_F9S6VKVIGUGz_6Ab2GK-csrNwmMz2YsQ2wNuRhSitiYZWx7G78MA7NKyqyTMjkps0rKfGbN6cZ4qnv0v4pNNPwHEECQaQ</recordid><startdate>200410</startdate><enddate>200410</enddate><creator>Aydin, M D</creator><creator>Dane, S</creator><creator>Gundogdu, C</creator><creator>Gursan, N</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>200410</creationdate><title>Neurodegenerative effects of monopolar electrocauterization on spinal ganglia in lumbar disc surgery</title><author>Aydin, M D ; Dane, S ; Gundogdu, C ; Gursan, N</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c356t-f721441d6fa6b84802bcc4166e0d31b57e86ea47d5cca528edddb330ce047fa73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Animals</topic><topic>Blood Vessels - enzymology</topic><topic>Blood Vessels - pathology</topic><topic>Blood Vessels - physiopathology</topic><topic>Cicatrix - etiology</topic><topic>Cicatrix - pathology</topic><topic>Cicatrix - physiopathology</topic><topic>Denervation - adverse effects</topic><topic>Disease Models, Animal</topic><topic>Diskectomy - adverse effects</topic><topic>Electrocoagulation - adverse effects</topic><topic>Ganglia, Spinal - anatomy & histology</topic><topic>Ganglia, Spinal - injuries</topic><topic>Ischemia - etiology</topic><topic>Ischemia - pathology</topic><topic>Ischemia - physiopathology</topic><topic>Lumbar Vertebrae - anatomy & histology</topic><topic>Lumbar Vertebrae - surgery</topic><topic>Male</topic><topic>Nerve Degeneration - etiology</topic><topic>Nerve Degeneration - pathology</topic><topic>Nerve Degeneration - physiopathology</topic><topic>Nerve Fibers, Myelinated - pathology</topic><topic>Nerve Fibers, Myelinated - physiology</topic><topic>Neurons, Afferent - pathology</topic><topic>Neurons, Afferent - physiology</topic><topic>Neurosurgical Procedures - adverse effects</topic><topic>Postoperative Complications - etiology</topic><topic>Postoperative Complications - physiopathology</topic><topic>Postoperative Complications - prevention & control</topic><topic>Rabbits</topic><topic>Spine</topic><topic>Zygapophyseal Joint - injuries</topic><topic>Zygapophyseal Joint - innervation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Aydin, M D</creatorcontrib><creatorcontrib>Dane, S</creatorcontrib><creatorcontrib>Gundogdu, C</creatorcontrib><creatorcontrib>Gursan, N</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Acta neurochirurgica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Aydin, M D</au><au>Dane, S</au><au>Gundogdu, C</au><au>Gursan, N</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Neurodegenerative effects of monopolar electrocauterization on spinal ganglia in lumbar disc surgery</atitle><jtitle>Acta neurochirurgica</jtitle><addtitle>Acta Neurochir (Wien)</addtitle><date>2004-10</date><risdate>2004</risdate><volume>146</volume><issue>10</issue><spage>1125</spage><epage>1129</epage><pages>1125-1129</pages><issn>0001-6268</issn><eissn>0942-0940</eissn><abstract>Monopolar electrocauterization (MEC) is widely used in spine surgery however electrical currents are hazardous for neural tissues, such as the spinal ganglia sited in the intervertebral foramina. We aimed to investigate the effects of MEC on spinal ganglia.
Fifteen male hybrid rabbits were included in the study. Three of the animals were used to analyze the findings regarding spinal ganglia without operation. The remaining animals underwent L4-5 disc surgery. For intra-operative facet denervation MEC was used for half of the animals. After one month, all animals were sacrificed and L5 spinal ganglia were removed for histopathological examination. The number and morphological changes of neurons in spinal ganglia were examined.
The mean number of live neurons was 22610 in non-operated rabbits; 21617 in the non-MEC group and 16692 in the MEC group. Neuronal degeneration was more prominent in the MEC group than in the non-MEC group.
MEC used during spine surgery may be injurious to spinal ganglia and should be used with caution.</abstract><cop>Austria</cop><pub>Springer Nature B.V</pub><pmid>15744848</pmid><doi>10.1007/s00701-004-0300-x</doi><tpages>5</tpages></addata></record> |
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| subjects | Animals Blood Vessels - enzymology Blood Vessels - pathology Blood Vessels - physiopathology Cicatrix - etiology Cicatrix - pathology Cicatrix - physiopathology Denervation - adverse effects Disease Models, Animal Diskectomy - adverse effects Electrocoagulation - adverse effects Ganglia, Spinal - anatomy & histology Ganglia, Spinal - injuries Ischemia - etiology Ischemia - pathology Ischemia - physiopathology Lumbar Vertebrae - anatomy & histology Lumbar Vertebrae - surgery Male Nerve Degeneration - etiology Nerve Degeneration - pathology Nerve Degeneration - physiopathology Nerve Fibers, Myelinated - pathology Nerve Fibers, Myelinated - physiology Neurons, Afferent - pathology Neurons, Afferent - physiology Neurosurgical Procedures - adverse effects Postoperative Complications - etiology Postoperative Complications - physiopathology Postoperative Complications - prevention & control Rabbits Spine Zygapophyseal Joint - injuries Zygapophyseal Joint - innervation |
| title | Neurodegenerative effects of monopolar electrocauterization on spinal ganglia in lumbar disc surgery |
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