Development and validation of a sensitive and selective method using GC/MS-MS for quantification of 5-fluorouracil in hospital wastewater

Pollution of the environment by pharmaceuticals is a subject of growing scientific and societal concern. However, few quantitative data have been reported concerning hospital wastewater contamination. Among the different molecules used at hospital, antineoplastic drugs appear to be of special intere...

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Veröffentlicht in:	Analytical and bioanalytical chemistry 2009-08, Vol.394 (8), p.2203-2212
Hauptverfasser:	Mullot, Jean-Ulrich, Karolak, Sara, Fontova, Anne, Huart, Bruno, Levi, Yves
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis methods Analytical Chemistry Antimetabolites, Antineoplastic - analysis Applied sciences Biochemistry Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Chromatographic methods and physical methods associated with chromatography Contamination Exact sciences and technology Fluorouracil - analysis Food Science Gas chromatographic methods Gas Chromatography-Mass Spectrometry - methods Global environmental pollution Hospitals Laboratory Medicine Mathematical analysis Mathematical models Models, Chemical Monitoring/Environmental Analysis Monitors Natural water pollution Original Paper Pharmaceuticals Pollution Pollution abatement Sensitivity and Specificity Solid Phase Extraction - methods Spectrometric and optical methods Waste Disposal, Fluid Waste water Water - analysis Water Pollutants, Chemical - analysis Water treatment and pollution
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