Prostate cancer segregation analyses using 4390 families from UK and Australian population-based studies

Familial aggregation of prostate cancer is likely to be due to multiple susceptibility loci, perhaps acting in conjunction with shared lifestyle risk factors. Models that assume a single mode of inheritance may be unrealistic. We analyzed genetic models of susceptibility to prostate cancer using seg...

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Veröffentlicht in:	Genetic epidemiology 2010-01, Vol.34 (1), p.42-50
Hauptverfasser:	MacInnis, Robert J., Antoniou, Antonis C., Eeles, Rosalind A., Severi, Gianluca, Guy, Michelle, McGuffog, Lesley, Hall, Amanda L., O'Brien, Lynne T., Wilkinson, Rosemary A., Dearnaley, David P., Ardern-Jones, Audrey T., Horwich, Alan, Khoo, Vincent S., Parker, Christopher C., Huddart, Robert A., McCredie, Margaret R., Smith, Charmaine, Southey, Melissa C., Staples, Margaret P., English, Dallas R., Hopper, John L., Giles, Graham G., Easton, Douglas F.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult Children Aged Aged, 80 and over Australia Case-Control Studies Fathers Genes, Recessive genetic Genetic Predisposition to Disease genetics Genetics, Population Humans Male Middle Aged Models, Genetic multifactorial inheritance pedigree prostatic neoplasms Prostatic Neoplasms - genetics Risk Factors Siblings United Kingdom
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