Interactions of Phospholipid Bilayer with Chitosan: Effect of Molecular Weight and pH

Chitosan has demonstrated its potentials as a gene carrier and a membrane perturbant for subsequent drug delivery to cells. However, there is currently a lack of experimental correlation between the physiochemical properties of chitosan and the resulting degree of lipid bilayer destabilization. In t...

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Veröffentlicht in:	Biomacromolecules 2001, Vol.2 (4), p.1161-1168
Hauptverfasser:	Fang, Ning, Chan, Vincent, Mao, Hai-Quan, Leong, Kam W
Format:	Artikel
Sprache:	eng
Schlagworte:	1,2-Dipalmitoylphosphatidylcholine - chemistry 1,2-Dipalmitoylphosphatidylcholine - metabolism Calorimetry, Differential Scanning Cell Membrane Permeability - drug effects Chitin - analogs & derivatives Chitin - chemistry Chitin - metabolism Chitin - pharmacology Chitosan Hydrogen-Ion Concentration Lipid Bilayers - chemistry Lipid Bilayers - metabolism Liposomes - chemistry Liposomes - metabolism Molecular Weight Solvents - pharmacology Spectroscopy, Fourier Transform Infrared Water - pharmacology
Online-Zugang:	Volltext
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