Surface Properties of Dioleoyl-sn-glycerol-3-ethylphosphocholine, a Cationic Phosphatidylcholine Transfection Agent, Alone and in Combination with Lipids or DNA

Long-chain cationic amphipaths are routinely used for transfecting DNA into cells, although the mechanism of DNA delivery by these agents is poorly understood. Since their interfacial properties are undoubtedly involved at some stage in the process, a comprehensive study of the surface behavior of a...

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Veröffentlicht in:	Langmuir 2006-03, Vol.22 (6), p.2770-2779
Hauptverfasser:	MacDonald, Robert C, Gorbonos, Alex, Momsen, Maureen M, Brockman, Howard L
Format:	Artikel
Sprache:	eng
Schlagworte:	Argon Chemistry Colloidal state and disperse state DNA - chemistry Exact sciences and technology General and physical chemistry Lipids - chemistry Membranes Phosphatidylcholines - chemistry Thermodynamics Transfection Water
Online-Zugang:	Volltext
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