A Mechanism for Incorporation of Galectin-3 into the Spliceosome through Its Association with U1 snRNP

Previously, we showed that galectin-1 and galectin-3 are redundant pre-mRNA splicing factors associated with the spliceosome throughout the splicing pathway. Here we present evidence for the association of galectin-3 with snRNPs outside of the spliceosome (i.e., in the absence of pre-mRNA splicing s...

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Veröffentlicht in:	Biochemistry (Easton) 2009-08, Vol.48 (32), p.7705-7712
Hauptverfasser:	Haudek, Kevin C, Voss, Patricia G, Locascio, Lauren E, Wang, John L, Patterson, Ronald J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Galectin 3 - genetics Galectin 3 - metabolism HeLa Cells Humans Macromolecular Substances - metabolism Ribonucleoprotein, U1 Small Nuclear - genetics Ribonucleoprotein, U1 Small Nuclear - metabolism RNA Precursors - genetics RNA Precursors - metabolism RNA Splicing Spliceosomes - genetics Spliceosomes - metabolism
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